Magnesium oil (also referred to as transdermal magnesium, magnesium hexahydrate) is a compound of

magnesium chloride Magnesium chloride is the family of inorganic compounds with the formula , where x can range from 0 to 12. These salts are colorless or white solids that are highly soluble in water. These compounds and their solutions, both of which occur in natu ...

dissolved in six molecules of

water Water (chemical formula ) is an Inorganic compound, inorganic, transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance, which is the main constituent of Earth's hydrosphere and the fluids of all known living ...

, with

magnesium Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a shiny gray metal having a low density, low melting point and high chemical reactivity. Like the other alkaline earth metals (group 2 of the periodic ta ...

as the

alkaline earth metal The alkaline earth metals are six chemical elements in group 2 of the periodic table. They are beryllium (Be), magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba), and radium (Ra).. The elements have very similar properties: they are all ...

and

chlorine Chlorine is a chemical element with the symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate between them. Chlorine i ...

as the nonmetal. In reality, it is not a "true" oil, as it is not composed of one or more

hydrocarbon In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon. Hydrocarbons are examples of group 14 hydrides. Hydrocarbons are generally colourless and hydrophobic, and their odors are usually weak or ...

s. Magnesium oil is actually magnesium chloride hexahydrate . Magnesium oil can be applied to the skin as an alternative to taking a magnesium supplement by mouth, and it is claimed to have health benefits, such as for the treatment of magnesium deficiency, to relieve muscle pain and ache (especially headaches), and to enhance relaxation. However, such use has been described as "scientifically unsupported" due to lack of any convincing data that magnesium is absorbed in significant amounts through the skin. It can also be found as a spray for the mentioned purposes. Magnesium is used in over 600 cellular reactions within the human body, including the immune system. Magnesium oil, with a chemical formula of has a formula mass of 203.30 g/mol.

Synthesis

When

(Mg) reacts with one molecule of

(), the

salt Salt is a mineral composed primarily of sodium chloride (NaCl), a chemical compound belonging to the larger class of salts; salt in the form of a natural crystalline mineral is known as rock salt or halite. Salt is present in vast quant ...

is forming. The electron deficient magnesium has a potential for further reactions to become stable. Dissolving this chemical,

(), in six molecules of

() results in the successful synthesis of "magnesium oil." The formation of magnesium oil, is depicted below:

Process of isolation

In a synthesis process known as the Dow process, magnesium chloride () is most commonly extracted from sea water by precipitating the molecule as

magnesium hydroxide Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2. It occurs in nature as the mineral brucite. It is a white solid with low solubility in water (). Magnesium hydroxide is a common component of antacids, such as milk ...

, followed by its conversion to the with the addition of

hydrochloric acid Hydrochloric acid, also known as muriatic acid, is an aqueous solution of hydrogen chloride. It is a colorless solution with a distinctive pungent smell. It is classified as a strong acid Acid strength is the tendency of an acid, symbol ...

(HCl( aq)). The solid-solid separation of from

NaCl Sodium chloride , commonly known as salt (although sea salt also contains other chemical salts), is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. With molar masses of 22.99 and 35.45 g/ ...

is accompanied by the usage of organic

solvent A solvent (s) (from the Latin '' solvō'', "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution. A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid. Water is a solvent for ...

s such as

tetrachloromethane Carbon tetrachloride, also known by many other names (such as tetrachloromethane, also recognised by the IUPAC, carbon tet in the cleaning industry, Halon-104 in firefighting, and Refrigerant-10 in HVACR) is an organic compound with the chemica ...

iodomethane Iodomethane, also called methyl iodide, and commonly abbreviated "MeI", is the chemical compound with the formula CH3I. It is a dense, colorless, volatile liquid. In terms of chemical structure, it is related to methane by replacement of one ...

, or the combination of these two organic solvents.

Past applications

Transdermal drug absorption has been part of human history for centuries from the time ancient Egyptians among other started using saunas. Magnesium delivered through the skin aids as a muscle relaxant and skin rejuvenation. Transdermal application of magnesium oil has been more popular than magnesium pills due to the ability of the oil to directly circulate through the bloodstream after its administration using skin-adhesive patches.

Toxicology

Those with kidney problems are advised to avoid using magnesium oil.

Synthesis

Process of isolation

Past applications

Toxicology

References

Further reading