Myosin-Ie (Myo1e) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''MYO1E''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Myosin-Ie is a long tailed myosin. It contains an N-terminal motor domain, an IQ motif, a TH1 domain containing a
plecstrin homology (PH) domain, a proline rich TH2 domain, and an
SH3 domain
The SRC Homology 3 Domain (or SH3 domain) is a small protein domain of about 60 amino acid residues. Initially, SH3 was described as a conserved sequence in the viral adaptor protein v-Crk. This domain is also present in the molecules of phos ...
.
The MYO1E gene was included in several genetic signatures for cancer prognosis.
References
Further reading
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