Minimum information about a microarray experiment (MIAME) is a standard created by the FGED Society for reporting

microarray A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon ...

experiments. MIAME is intended to specify all the information necessary to interpret the results of the

experiment An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into cause-and-effect by demonstrating what outcome occurs whe ...

unambiguously and to potentially reproduce the experiment. While the standard defines the content required for compliant reports, it does not specify the format in which this data should be presented. MIAME describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. There are a number of

file format A file format is a standard way that information is encoded for storage in a computer file. It specifies how bits are used to encode information in a digital storage medium. File formats may be either proprietary or free. Some file format ...

s used to represent this data, as well as both public and subscription-based repositories for such experiments. Additionally, software exists to aid the preparation of MIAME-compliant reports. MIAME revolves around six key components:

raw data Raw data, also known as primary data, are ''data'' (e.g., numbers, instrument readings, figures, etc.) collected from a source. In the context of examinations, the raw data might be described as a raw score (after test scores). If a scientist ...

, normalized data, sample annotations,

experimental design The design of experiments (DOE, DOX, or experimental design) is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associ ...

, array annotations, and data protocols.

References

{{Authority control Biochemistry detection methods Genetics techniques Microarrays