Homeobox protein Meis1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the MEIS1
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.
Interactions
MEIS1 has been shown to
interact with
PBX1
Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the ''PBX1'' gene.
Interactions
PBX1 has been shown to Protein-protein interaction, interact with:
* HOXB1,
* HOXB7,
* MEIS1, and
* PKNOX1, Prep1.
Referen ...
and
HOXA9.
References
Further reading
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External links
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Transcription factors
{{gene-2-stub