MBL deficiency is a pathology of the
innate immune system involving
Mannan-binding lectin pathway
The lectin pathway or lectin complement pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that, after activation, it proceeds through the action of C4 and C2 to produce acti ...
components such as
MBL2.
It is thought that 5–10% of the population have an MBL deficiency of some degree.
There are varying degrees of MBL deficiency; some people will not even know they have the deficiency, while others may have such low levels that they experience infections with great frequency. Babies and young children are most at risk.
References
External links
Complement deficiency
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