Lignum nephriticum
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''Lignum nephriticum'' (
Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...
for "kidney wood") is a traditional
diuretic A diuretic () is any substance that promotes diuresis, the increased production of urine. This includes forced diuresis. A diuretic tablet is sometimes colloquially called a water tablet. There are several categories of diuretics. All diuretics i ...
that was derived from the
wood Wood is a porous and fibrous structural tissue found in the stems and roots of trees and other woody plants. It is an organic materiala natural composite of cellulose fibers that are strong in tension and embedded in a matrix of lignin ...
of two
tree In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, including only woody plants with secondary growth, plants that are ...
species In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...
, the narra (''
Pterocarpus indicus ''Pterocarpus indicus'' (commonly known as Amboyna wood, Malay padauk, Papua New Guinea rosewood, Philippine mahogany, Andaman redwood, Burmese rosewood, narra and asana in the Philippines, angsana, or Pashu padauk) is a species of ''Pterocarpus ...
'') and the Mexican kidneywood (''
Eysenhardtia polystachya ''Eysenhardtia polystachya'', the kidneywood, is a tree from Mexico, growing along forest edges and water courses at elevations of 150–3000 m. Previously it was used as a source of lignum nephriticum. References * polystachya ...
''). The wood is capable of turning the color of water it comes in contact with into beautiful opalescent hues that change depending on light and angle, the earliest known record of the phenomenon of
fluorescence Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore a lower photon energy, tha ...
. Due to this strange property, it became well known in
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a subcontinent of Eurasia and it is located entirel ...
from the 16th to the early 18th century. Cups made from ''lignum nephriticum'' were given as gifts to royalty. Water drunk from such cups, as well as imported powders and extracts from ''lignum nephriticum'', were thought to have great medicinal properties. The ''lignum nephriticum'' derived from Mexican kidneywood was known as the ''coatli'', ''coatl'', or ''cuatl'' ("snake water") or ''tlapalezpatli'' ("blood-tincture medicine") in the Nahuatl language. It was traditionally used by the
Aztec people The Aztecs () were a Mesoamerican culture that flourished in central Mexico in the post-classic period from 1300 to 1521. The Aztec people included different ethnic groups of central Mexico, particularly those groups who spoke the Nahuatl l ...
as a diuretic prior to European contact. Similarly, the ''lignum nephriticum'' cups made from narra wood were part of the native industry of the
Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...
before the arrival of the
Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Can ...
. The cups were manufactured in southern
Luzon Luzon (; ) is the largest and most populous island in the Philippines. Located in the northern portion of the Philippines archipelago, it is the economic and political center of the nation, being home to the country's capital city, Manila, as ...
, particularly in the Naga region. The name of which was derived from the abundance of the narra trees, which was known as '' naga'' in the
Bikol language The Bikol languages or Bicolano languages are a group of Central Philippine languages spoken mostly in the Bicol Peninsula in the island of Luzon, the neighboring island province of Catanduanes and the island of Burias in Masbate. Internal ...
(literally "serpent" or "dragon").


History

The first known description of the medicine appears in the ''Historia general de las cosas de la Nueva España'' (1560–1564) by the Spanish
Franciscan , image = FrancescoCoA PioM.svg , image_size = 200px , caption = A cross, Christ's arm and Saint Francis's arm, a universal symbol of the Franciscans , abbreviation = OFM , predecessor = , ...
missionary A missionary is a member of a religious group which is sent into an area in order to promote its faith or provide services to people, such as education, literacy, social justice, health care, and economic development.Thomas Hale 'On Being a Mi ...
and
ethnographer Ethnography (from Greek ''ethnos'' "folk, people, nation" and ''grapho'' "I write") is a branch of anthropology and the systematic study of individual cultures. Ethnography explores cultural phenomena from the point of view of the subject o ...
Bernardino de Sahagún Bernardino de Sahagún, OFM (; – 5 February 1590) was a Franciscan friar, missionary priest and pioneering ethnographer who participated in the Catholic evangelization of colonial New Spain (now Mexico). Born in Sahagún, Spain, in 1499, ...
. In the most famous surviving manuscripts of the work, the
Florentine Codex The ''Florentine Codex'' is a 16th-century ethnographic research study in Mesoamerica by the Spanish Franciscan friar Bernardino de Sahagún. Sahagún originally titled it: ''La Historia General de las Cosas de Nueva España'' (in English: ''Th ...
, Sahagún called it by its Nahuatl name, ''coatli'', given by
Aztec The Aztecs () were a Mesoamerican culture that flourished in central Mexico in the post-classic period from 1300 to 1521. The Aztec people included different ethnic groups of central Mexico, particularly those groups who spoke the Nahuatl ...
healers. He described its unusual property of turning the color of water that comes in contact with it to bright blue: "''...patli, yoan aqujxtiloni, matlatic iniayo axixpatli'' ..it is a medicine, and makes the water of blue color, its juice is medicinal for the urine. The
Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Can ...
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and botanist Nicolás Monardes also independently described the medicine in his 1565 work ''
Historia medicinal de las cosas que se traen de nuestras Indias Occidentales ''Historia medicinal de las cosas que se traen de nuestras Indias Occidentales'' ("Medical study of the products imported from our West Indian possessions") is the standard title for a survey by Nicolás Monardes (1493–1588), Spanish physician ...
''. He is the origin of the name ''lignum nephriticum'', due to the use of the wood to treat
liver The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it ...
and
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blo ...
ailments in New Spain. He described the wood as white in color. It was prepared by being sliced into very thin chips. The chips were then placed in clear spring water. After about half an hour, the water starts to turn a very pale blue, turning bluer as time passes. The water is then drunk neat or mixed with wine. He observed that despite the change in color, the wood itself imparts no taste to the water. In 1570,
Francisco Hernández de Toledo Francisco Hernández de Toledo (1514 in La Puebla de Montalbán, Toledo – 28 January 1587 in Madrid) was a naturalist and court physician to the King of Spain. Hernández was among the first wave of Spanish Renaissance physicians practicing acc ...
, the court
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
of King Philip II of Spain, led what is considered the first scientific expedition to the
Americas The Americas, which are sometimes collectively called America, are a landmass comprising the totality of North and South America. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along with th ...
. When he returned to Spain in 1577, he gave testimony of the medicinal properties of ''lignum nephriticum'', as described by Monardes. However, he expressed uncertainty as to its origin, stating that while he was told the source plant was a shrub, he had personally also witnessed specimens that reached the size of very large trees. In 1646,
Athanasius Kircher Athanasius Kircher (2 May 1602 – 27 November 1680) was a German Jesuit scholar and polymath who published around 40 major works, most notably in the fields of comparative religion, geology, and medicine. Kircher has been compared to fe ...
, a
German German(s) may refer to: * Germany (of or related to) ** Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Ge ...
Jesuit
scholar A scholar is a person who pursues academic and intellectual activities, particularly academics who apply their intellectualism into expertise in an area of study. A scholar can also be an academic, who works as a professor, teacher, or researc ...
residing in
Rome , established_title = Founded , established_date = 753 BC , founder = King Romulus (legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption ...
, published an account of his experiments on ''lignum nephriticum'' in his work '' Ars Magna Lucis et Umbræ''. He conducted his experiments on a cup given to him as a gift from Jesuit missionaries in
Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...
. He commented that while previous authors only described the color of the water mixed with ''lignum nephriticum'' as blue, his own experiments actually showed that the wood turned the water into all kinds of colors, depending on the light. He later presented the cup to the Holy Roman Emperor, Ferdinand III. A second cup was described by in 1650 by the Swiss botanist
Johann Bauhin Johann (or Jean) Bauhin (12 December 1541 – 26 October 1613) was a Swiss botanist, born in Basel. He was the son of physician Jean Bauhin and the brother of physician and botanist Gaspard Bauhin. Biography Bauhin studied botany at the Univers ...
in his great work ''Historia plantarum universalis''. He had received it under the name ''palum indianum'' from a colleague. Unlike the wood in Monardes' account, the wood the cup was made from was reddish in color. It was a handspan in diameter, about , and adorned with variegated lines. Shavings from the same wood were included with the cup. Bauhin observed that when water was poured into the cup with the wood shavings, the water shortly turned into "a wonderful blue and yellow color, and when held up against the light beautifully resembled the varying color of the opal, giving forth reflections, as in that gem, of fiery yellow, bright red, glowing purple, and sea green most wonderful to behold." Bauhin believed that the wood was taken from a species of ash ('' Fraxinus''). In 1664,
Robert Boyle Robert Boyle (; 25 January 1627 – 31 December 1691) was an Anglo-Irish natural philosopher, chemist, physicist, alchemist and inventor. Boyle is largely regarded today as the first modern chemist, and therefore one of the founders of ...
explained the phenomenon to be dependent on pH. In an unpublished paper in 1665,
Sir Isaac Newton Sir Isaac Newton (25 December 1642 – 20 March 1726/27) was an English mathematician, physicist, astronomer, alchemist, theologian, and author (described in his time as a " natural philosopher"), widely recognised as one of the g ...
first mentioned the cups in the paper "Of Colours". He later also mentioned in 1672, in his theories of light and color. However, the botanical origin of wood used in ''lignum nephriticum'' was eventually lost in the late 18th century.


Modern studies

In 1915, the source of the wood was rediscovered by the American botanist
William Edwin Safford William Edwin Safford (December 14, 1859, Chillicothe, Ohio – January 10, 1926) was an American botanist, ethnologist, and educator employed by the U.S. Navy and federal government. Safford graduated from the U.S. Naval Academy in 1880 and pursu ...
. He deduced that ''lignum nephriticum'' actually came from two species of trees that became confused as one. He identified the original traditional remedy described by Monardes as Mexican kidneywood, a native of
Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...
, while the cups which became famous in Europe were originally carved from narra wood by the inhabitants of southern
Luzon Luzon (; ) is the largest and most populous island in the Philippines. Located in the northern portion of the Philippines archipelago, it is the economic and political center of the nation, being home to the country's capital city, Manila, as ...
from the
Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...
. It was imported into Mexico through the
Manila-Acapulco Galleon fil, Galyon ng Maynila , english_name = Manila Galleon , duration = From 1565 to 1815 (250 years) , venue = Between Manila and Acapulco , location = New Spain (Spanish Empire ...
trade and from there, introduced to Europe. Both species are members of the legume
family Family (from la, familia) is a group of people related either by consanguinity (by recognized birth) or affinity (by marriage or other relationship). The purpose of the family is to maintain the well-being of its members and of society. Idea ...
Fabaceae. It is now known that Sahagún's and Monardes' accounts are the earliest known records of the phenomenon of
fluorescence Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore a lower photon energy, tha ...
. The unusual property of the wood was caused by the compound matlaline, which is the
oxidation Redox (reduction–oxidation, , ) is a type of chemical reaction in which the oxidation states of substrate change. Oxidation is the loss of electrons or an increase in the oxidation state, while reduction is the gain of electrons or a ...
product of one of the flavonoids found in the wood. The phenomenon is also exhibited by other members of the family Fabaceae.


See also

* Bologna Stone *''
Silphium Silphium (also known as ''silphion'', ''laserwort'', or ''laser'') is an unidentified plant that was used in classical antiquity as a seasoning, perfume, aphrodisiac, and medicine. It also was used as a contraceptive by ancient Greeks and Romans ...
'' *
Lignum vitae Lignum vitae () is a wood, also called guayacan or guaiacum, and in parts of Europe known as Pockholz or pokhout, from trees of the genus ''Guaiacum''. The trees are indigenous to the Caribbean and the northern coast of South America (e.g: Col ...


References


External links

*{{Commons category-inline, Lignum nephriticum, ''Lignum nephriticum'' Traditional medicine Wood