LIM domain only protein 3 is a transcription co-factor, which in humans is encoded by the ''LMO3''

gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...

. LMO3 interacts with the tumor suppressor

p53 p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers. The p53 proteins (originally thought to be, and often s ...

and regulates its function. LMO3 is considered to be an oncogene in Neuroblastoma.

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Further reading