''Ligilactobacillus salivarius'' is a probiotic bacteria species that has been found to live in the

gastrointestinal tract The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organ (biology), organs of the digestive syste ...

and exert a range of therapeutic properties including suppression of pathogenic bacteria.

Therapeutic research

Irritable bowel syndrome

''Ligilactobacillus salivarius'' has been found to be of benefit in the alleviation of the symptom

flatulence Flatulence, in humans, is the expulsion of gas from the intestines via the anus, commonly referred to as farting. "Flatus" is the medical word for gas generated in the stomach or bowels. A proportion of intestinal gas may be swallowed environm ...

in individuals suffering from irritable bowel syndrome.

Pancreatic necrosis

Pancreatic necrosis Acute pancreatitis (AP) is a sudden inflammation of the pancreas. Causes in order of frequency include: 1) a gallstone impacted in the common bile duct beyond the point where the pancreatic duct joins it; 2) heavy alcohol use; 3) systemic disease; ...

, if left untreated, has an almost 100 percent fatality rate due to

bacterial translocation Intestinal permeability is a term describing the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall, into the rest of the body. The intestine normally exhibits some permeability, which allows ...

. ''Ligilactobacillus salivarius'' has been found to have a wide spectrum of coverage against pathogenic organisms that translocate from the

thereby demonstrating therapeutic benefit in the management of pancreatic necrosis. Research has shown that the addition of this species along with other probiotic species (specifically ''

Bifidobacterium bifidum ''Bifidobacterium bifidum'' is a bacterial species of the genus ''Bifidobacterium''. ''B. bifidum'' is one of the most common probiotic bacteria that can be found in the body of mammals, including humans. Structure and characteristics ''B. bifi ...

'', ''

Bifidobacterium infantis ''Bifidobacterium longum'' is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the 32 species that belong to the genus ''Bifidobacterium''. It is a microaerotolerant anaerobe and con ...

'', '' Lactobacillus acidophilus'', ''

Lacticaseibacillus casei ''Lacticaseibacillus casei ''is an organism that belongs to the largest genus in the family ''Lactobacillaceae'', a lactic acid bacteria (LAB), that was previously classified as ''Lactobacillus casei-01''. This bacteria has been identified as facu ...

'', and '' Lactococcus lactis'') suppressed pro- inflammatory

cytokines Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are peptides and cannot cross the lipid bilayer of cells to enter the cytoplasm. Cytokines have been shown to be involved in autocrin ...

and further suppressed bacterial overgrowth in the

small intestine The small intestine or small bowel is an organ in the gastrointestinal tract where most of the absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the p ...

leading to a reduction in bacterial translocation.

Atopic dermatitis

Atopic dermatitis symptoms have been shown to be reversed in some children.

References

External links

Type strain of ''Lactobacillus salivarius'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
{{Taxonbar, from=Q3825336 Lactobacillaceae Bacteria described in 1953