Kemerovo tickborne viral fever
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Kemerovo tickborne viral fever is an aparalytic
febrile Fever, also referred to as pyrexia, is defined as having a temperature above the normal range due to an increase in the body's temperature set point. There is not a single agreed-upon upper limit for normal temperature with sources using valu ...
illness accompanied by
meningism Meningism is a set of symptoms similar to those of meningitis but not caused by meningitis. Whereas meningitis is inflammation of the meninges (membranes that cover the central nervous system), meningism is caused by nonmeningitic irritation of t ...
following tick-bite. The causative agent is a zoonotic
Orbivirus ''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily ''Sedoreovirinae''. Unlike other reoviruses, orbiviruses are arboviruses. They can infect and replicate within a wide range of arthropod and verte ...
first described in 1963 in western
Siberia Siberia ( ; rus, Сибирь, r=Sibir', p=sʲɪˈbʲirʲ, a=Ru-Сибирь.ogg) is an extensive geographical region, constituting all of North Asia, from the Ural Mountains in the west to the Pacific Ocean in the east. It has been a part of ...
by Mikhail Chumakov and coworkers. The virus has some 23
serotypes A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or cells are classified together based on their surface antigens, allowing the epi ...
, and can occur in
coinfections Coinfection is the simultaneous infection of a host (biology), host by multiple pathogens, pathogen species. In virology, coinfection includes simultaneous infection of a single cell (biology), cell by two or more virus particles. An example is th ...
with other
Orbivirus ''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily ''Sedoreovirinae''. Unlike other reoviruses, orbiviruses are arboviruses. They can infect and replicate within a wide range of arthropod and verte ...
es and tick-transmitted
encephalitis Encephalitis is inflammation of the brain. The severity can be variable with symptoms including reduction or alteration in consciousness, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, ...
viruses, complicating the course of illness. Rodents and birds are the primary
vertebrate Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, ...
hosts of the virus; ''
Ixodes persulcatus ''Ixodes persulcatus'', the taiga tick, is a species of hard-bodied tick distributed from Europe through central and northern Asia to the People’s Republic of China and Japan. The sexual dimorphism of the species is marked, the male being much ...
'' ticks are a vector of the virus. Kemerovo and related viruses may be translocated distances in the environment by migratory birds.


References

{{DEFAULTSORT:Kemerovo tickborne viral fever Orbiviruses Arthropod-borne viral fevers and viral haemorrhagic fevers