Katherine Flegal
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Katherine Mayhew Flegal is an American epidemiologist and senior scientist at the
Center for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
's National Center for Health Statistics. She is one of the most highly cited scientists in the field of the epidemiology of obesity according to Thomson ReutersKatherine Flegal Interview
/ref> and has been called "one of the great epidemiologists" by former FDA Commissioner
David A. Kessler David Aaron Kessler (born May 13, 1951) is an American pediatrician, attorney, author, and administrator (both academic and governmental) serving as Chief Science Officer of the White House COVID-19 Response Team since 2021. Kessler was the commi ...
.


Education and career

Flegal was born in
Berkeley, California Berkeley ( ) is a city on the eastern shore of San Francisco Bay in northern Alameda County, California, United States. It is named after the 18th-century Irish bishop and philosopher George Berkeley. It borders the cities of Oakland and E ...
, where she grew up. She earned a bachelor's degree in anthropology from the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...
(UC) in 1967 and lived in
Turkey Turkey ( tr, Türkiye ), officially the Republic of Türkiye ( tr, Türkiye Cumhuriyeti, links=no ), is a transcontinental country located mainly on the Anatolian Peninsula in Western Asia, with a small portion on the Balkan Peninsula in ...
for 7 months. Following that she had a job as a programmer trainee at the
Alameda County Alameda County ( ) is a county located in the U.S. state of California. As of the 2020 census, the population was 1,682,353, making it the 7th-most populous county in the state and 21st most populous nationally. The county seat is Oakland. Alam ...
Data Processing Center and became responsible for its
food stamp program In the United States, the Supplemental Nutrition Assistance Program (SNAP), formerly known as the Food Stamp Program, is a federal program that provides food-purchasing assistance for low- and no-income people. It is a federal aid program, ad ...
. This gave her extensive experience in data management, coding, and record keeping. After three years and some community college courses in chemistry and biology, Flegal returned to UC to earn a second bachelor’s degree, in food and nutrition. Next Flegal completed Master's and Ph.D. degrees at
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to tea ...
, expanding her interests in statistics and epidemiology and receiving her Ph.D. in 1982. When a post-doctoral position at the
University of Pittsburgh The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the univers ...
offered little opportunity for research, Flegal completed a second master's degree there, in
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
(MPH). In 1987, after working at the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
's biostatistics department, Flegal began working at the
Centers for Disease Control The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
(CDC).


Research

Flegal is well known for a series of influential and highly cited articles on the prevalence of obesity in U.S. children and adults. In 1994, Flegal and her CDC co-authors were among the first to publish data indicating that the percentage of overweight people in the United States had been increasing from the 1980s onwards. Their paper appeared in the '' Journal of the American Medical Association'' (''JAMA''). In addition, she was a major contributor to the development of the 2000 CDC growth charts, used in the U.S. to assess the growth patterns of infants and children. In 2005 Flegal and co-authors from CDC and NIH published a study in ''JAMA'' which found that being overweight was associated with lower mortality than normal weight and that obesity was associated with slightly higher mortality. The study received considerable opposition, in part because its conclusions differed from those of another paper published by senior CDC authors in March 2004. After considerable discussion, the CDC accepted Flegal's figures as correct. Flegal herself has stated "Our paper was straightforward and defensible, used only publicly available data, and corrected the errors in several previous papers on the topic". Flegal's article received CDC's highest science award, the Charles C. Shepard award, in 2006. In 2013, Flegal was the lead author of a systematic review and
meta-analysis A meta-analysis is a statistical analysis that combines the results of multiple scientific studies. Meta-analyses can be performed when there are multiple scientific studies addressing the same question, with each individual study reporting me ...
published in ''JAMA'' regarding the association of overweight and obesity with mortality. In a large sample, drawn from other countries as well as the U.S., overweight people had lower mortality relative to people of normal weight. The work examined the results of 97 studies that had included 2.88 million people.


Reaction

Flegal's work has been criticized by
Walter Willett Walter C. Willett (born June 20, 1945) is an American physician and nutrition researcher. Currently, Willett is the Fredrick John Stare Professor of Epidemiology and Nutrition at the Harvard School of Public Health and was the chair of its depart ...
of the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard- MIT School for Health Officers, the nation's firs ...
, who called her 2013 meta-analysis paper a "pile of rubbish ... No one should waste their time reading it." Willett was subsequently admonished for his unseemly behavior towards Flegal in an editorial and feature article in ''
Nature Nature, in the broadest sense, is the physical world or universe. "Nature" can refer to the phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. Although humans are ...
'', one of the world's pre-eminent scientific journals. Jeffrey Scott Flier, the dean of
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
, convened a panel of experts to discuss the paper at Harvard on February 20, 2013. The panel's members suggested that Flegal's meta-analysis paper contained methodological errors, and criticized the selection criteria used for washing out too many people. Harvard's own subsequent analysis supported its position, but also received criticisms over how the researchers determined who to include. Many researchers accept the results of Flegal's 2005 and 2013 papers and see them as an illustration of what is known as the "
obesity paradox The obesity paradox is the finding in some studies of a lower mortality rate for overweight or obese people within certain subpopulations. The paradox has been observed in people with cardiovascular disease and cancer. Explanations for the paradox ...
". In 2021 Diana Thomas described Flegal's 2013 meta-analysis as "the gold standard" of obesity research. In 2021, Flegal published a paper about her experiences with her 2005 and 2013 papers, concluding "Scientific findings should be evaluated on their merits, not on the basis of whether they fit a desired narrative."


References


External links

* {{DEFAULTSORT:Flegal, Katherine American women epidemiologists American epidemiologists UC Berkeley College of Letters and Science alumni Cornell University alumni University of Pittsburgh School of Public Health alumni Living people Centers for Disease Control and Prevention people Obesity researchers Year of birth missing (living people) 21st-century American women