Krishna Balaji Sainis (born 2 October 1949) is an Indian immunologist. He is a former senior professor of Life Sciences at

Homi Bhabha National Institute The Homi Bhabha National Institute (HBNI) is an Indian deemed university established by the Department of Atomic Energy, which unifies academic programmes of several of its constituent institutions. Deemed universities in India have been divi ...

and an elected fellow of the

National Academy of Sciences, India The National Academy of Sciences, India, established in 1930, is the oldest science academy in India. It is located in Prayagraj, Uttar Pradesh. Prof. Meghnad Saha was the founder president. Fellows *Suddhasatwa Basu * Sudha Bhattacharya * Ch ...

. Since 1999, he has served as the Indian representative on the

United Nations Scientific Committee on the Effects of Atomic Radiation The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) was set up by resolution of the United Nations General Assembly in 1955. 21 states are designated to provide scientists to serve as members of the committee which ...

. The

Council of Scientific and Industrial Research The Council of Scientific and Industrial Research ( IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the ...

, the apex agency of the Government of India for scientific research, awarded him the

Shanti Swarup Bhatnagar Prize for Science and Technology The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, applied or fundamental, in biology, ...

for his contributions to medical sciences in 1994.

Biography

Born on 2 October 1949, K. B. Sainis earned a master's degree in biochemistry (MSc) from Savitribai Phule Pune University and did a one-year course in biology and radiobiology at

Bhabha Atomic Research Centre The Bhabha Atomic Research Centre (BARC) is India's premier nuclear research facility, headquartered in Trombay, Mumbai, Maharashtra, India. It was founded by Homi Jehangir Bhabha as the Atomic Energy Establishment, Trombay (AEET) in January 1 ...

(BARC). Upon completion of the course in 1972, he joined BARC as a Scientific Officer while continuing his doctoral studies at Pune University and secured a PhD in biophysics in 1980. Taking a sabbatical, he did his post-doctoral studies at the New England Medical Centre of

Tufts University School of Medicine The Tufts University School of Medicine is the medical school of Tufts University, a private research university in Massachusetts. It was established in 1893 and is located on the university's health sciences campus in downtown Boston. The '' ...

and, with the assistance of an

IAEA The International Atomic Energy Agency (IAEA) is an intergovernmental organization that seeks to promote the peaceful use of nuclear energy and to inhibit its use for any military purpose, including nuclear weapons. It was established in 195 ...

fellowship, he completed his studies at

University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...

at its ICRF Tumor Immunology Unit. Returning to BARC, he served in many positions, heading the Immunology Section and the Cell Biology Division and serving as the associate director of the Bioscience Group. He became director of the Bio-Medical Group in 2006, with the responsibility of six divisions. During his service at BARC, he has also been working as a faculty at the department of Life Sciences of the

where he is a senior professor. Sainis is married to Jayashree Krishna Sainis, a biochemist, and the family lives in

Navi Mumbai Navi Mumbai (), is a planned city situated on the west coast of the Indian subcontinent, located in the Konkan division of Maharashtra state, on the mainland of India. Navi Mumbai is part of the Mumbai Metropolitan Region (MMR). The city i ...

Research

Sainis' studies in immunobiology have covered how

T Cells A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell re ...

and their receptors influence immune response to DNA in

mycobacterial ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and ...

antigen In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune respons ...

s and

lupus nephritis Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE), an autoimmune disease. It is a type of glomerulonephritis in which the glomeruli become inflamed. Since it is a result of SLE, this type of glomerulo ...

, an autoimmune disease. He headed a group of scientists at BARC who were involved in research on

immunomodulators Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherap ...

based on plants. His studies have been documented and cited in texts and articles.uthor"> He has also written chapters in books published by others.

Affiliations and memberships

Sainis has been associated with two international agencies. He served as president of the Standing Advisory Group on Nuclear Applications (SAGNA) of the International Atomic Energy Agency (IAEA) in 2012, and since 1999 has served as the Indian representative on the

. Sainis is the president of the Mumbai Immunology Group at Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) of the

Tata Memorial Centre The Tata Memorial Hospital is situated in Parel, Mumbai, in India. Also popularly known as TMH. It is a specialist cancer treatment and research centre, closely associated with the Advanced Centre for Treatment, Research and Education in Cancer ...

and a former vice president of the Maharashtra Academy of Sciences. He is an honorary adviser to the Society for Free Radical Research India (SFRR-India); a member of the Advisory Committee of the ''National Training Program on Radiation Processing of Food for Food and Quarantine Inspectors & Quality Control Personnel'' organized by Department of Atomic Energy in association with BARC in February 2013; and a member of the Indian Immunology Society. He was previously associated with ongoing education programs such as the XVII Training Workshop on Radiation Emergency Preparedness for Medical Officers, the Refresher Course 2013 of the Indian Women Scientists Association, and the AKRUTI Technology Package for Rural Deployment of BARC. He has delivered several invited speeches or keynote addresses and is a reviewer for Hindawi journals.

Awards and honors

The

awarded Sainis the

Shanti Swarup Bhatnagar Prize The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, applied or fundamental, in biology, ...

, one of the highest Indian science awards, in 1994. The

elected him as a fellow in 2002. He is also an elected fellow of the Maharashtra Academy of Sciences.

Biography

Research

Affiliations and memberships

Awards and honors

Selected bibliography

Chapters

Articles

See also

Notes

References

External links

Further reading