John Stein (physiologist)
   HOME

TheInfoList



OR:

John Frederick Stein is a British
physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
. He is a
fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...
of
Magdalen College, Oxford Magdalen College (, ) is a constituent college of the University of Oxford. It was founded in 1458 by William of Waynflete. Today, it is the fourth wealthiest college, with a financial endowment of £332.1 million as of 2019 and one of the ...
, and holds a professorship in physiology at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
. He has research interests in the neurological basis of
dyslexia Dyslexia, also known until the 1960s as word blindness, is a disorder characterized by reading below the expected level for one's age. Different people are affected to different degrees. Problems may include difficulties in spelling words, r ...
.


Life

A doctor of philosophy, Stein became a research biologist and neurologist and took up a teaching career. He is active in furthering the medical benefits of animal testing, speaking at pro-testing rallies and demonstrations, and has defended animal testing in high-profile television interviews. He is the chair of the Dyslexia Research Trust and is a proponent of the magnocellular theory of dyslexia. He has supervised many medical and physiology students at the University conducting laboratory work investigating the theory. He is a trustee of the
Institute for Food, Brain and Behaviour The Institute for Food, Brain and Behaviour ("IFBB") is a Registered Charity with the primary focus of commissioning research into how food, nutrition and diet can affect brain function and behaviour. Trustees include France Jackson (Chairman) and ...
and Chair of the Institute's Science Advisory Council. Stein came into the public eye when Gordon Brown suggested a student had been discriminated against because of her state school education. This was despite the fact that she had comparable qualifications to the accepted applicants, who came from a broad range of backgrounds. Stein is the brother of the chef Rick Stein, and the uncle of the DJ
Judge Jules Julius O'Riordan (born 1966), better known by his stage name Judge Jules, is a British dance music DJ, record producer and entertainment lawyer. He is known for his DJ activities, music production and long-running radio show which achieved glob ...
. Stein was elected as a Fellow of the
Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to adv ...
in 2014.


Deep brain stimulation

Along with Tipu Aziz and
Kevin Warwick Kevin Warwick (born 9 February 1954) is an English engineer and Deputy Vice-Chancellor (Research) at Coventry University. He is known for his studies on direct interfaces between computer systems and the human nervous system, and has also don ...
, Stein is presently working on an intelligent
Deep brain stimulation Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus ...
system for
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms beco ...
.


Dyslexia research

Alongside his former D.Phil. student, Joe Taylor, Stein has advocated a new theory of central noradrenergic deficiency in Dyslexia. Taylor and Stein have proposed that increasing noradrenergic output from the
locus coeruleus The locus coeruleus () (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic. It is a part of the reticular activating system. The locus coer ...
via a subcortical irradiance detection pathway may prove effective in the treatment of the condition.Taylor, Visser and Stein. The efficacy of spectral filters in the upregulation of retinohypothalamic drive. Program No. 927.13. 2007. San Diego, CA: Society for Neuroscience, 2007.


References


External links


Homepage of Professor John Stein

Dyslexia Research Trust

Institute for Food, Brain and Behaviour
{{DEFAULTSORT:Stein, John Fellows of Magdalen College, Oxford English people of German descent Living people Dyslexia researchers Year of birth missing (living people) British neurologists Fellows of the Academy of Medical Sciences (United Kingdom)