Jacques-Joseph Grancher (; 29 September 1843 in Felletin, Creuse – 13 July 1907) was a French

pediatrician Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...

born in Felletin. In 1862 he began his medical studies in

Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. Si ...

, where he worked as an assistant at the Hôpital des Enfants Malades (under Eugène Bouchut), the Hôpital de la Charité, the Hôpital de la Pitié and Lariboisière Hospital (under

Paul Jules Tillaux Paul Jules Tillaux (8 December 1834 – 20 October 1904) was a French physician who was a native of Aunay-sur-Odon, département Calvados. Tillaux was a surgeon and professor of surgery in Paris, and in 1879 became a member of the '' Académie ...

). He learned

histological Histology, also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures vis ...

techniques with

Louis-Antoine Ranvier Louis-Antoine Ranvier (2 October 1835 – 22 March 1922) was a French physician, pathologist, anatomist and histologist, who discovered the nodes of Ranvier, regularly spaced discontinuities of the myelin sheath, occurring at varying intervals ...

and Victor André Cornil in their private laboratory on ''Rue Christine'', and for several years served as director of a

pathological Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in th ...

anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having i ...

laboratory in

Clamart Clamart () is a commune in the southwestern suburbs of Paris, France. It is located from the centre of Paris. The town is divided into two parts, separated by a forest: ''bas Clamart'', the historical centre, and ''petit Clamart'' with urbani ...

(1868–1878). From 1885 until his death in 1907, he was director of Hôpital des Enfants Malades. In 1900 he was elected vice-chairman of the board of directors at the

Pasteur Institute The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vacc ...

. Grancher is remembered for his research of

tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, ...

. He was a pioneer in the creation of safeguards for the prevention of childhood tuberculosis, and was an advocate of isolation and

antisepsis An antiseptic (from Greek ἀντί ''anti'', "against" and σηπτικός ''sēptikos'', "putrefactive") is an antimicrobial substance or compound that is applied to living tissue/ skin to reduce the possibility of infection, sepsis, or pu ...

in the fight against the disease. In 1897 with

Jules Comby Jules Comby (; 28 April 1853, in Arnac-Pompadour – 18 March 1947) was a French pediatrician. The eponymous "Comby's sign" is named after him, which is an early indication of measles characterized by thin whitish patches on the gums and buccal ...

(1853–1947) and

Antoine Marfan Antoine Bernard-Jean Marfan (; June 23, 1858 – February 11, 1942) was a French paediatrician. He was born in Castelnaudary (département Aude, Languedoc-Roussillon) to Antoine Prosper Marfan and Adélaïde Thuries. He began his medical studie ...

(1858–1942), he published "''Traité des maladies de l’enfance''" (Treatise of the Diseases of Childhood). In 1885, Grancher and Alfred Vulpian (1826–1887) were instrumental in convincing

Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named afte ...

(1822–1895) to perform the first successful

vaccination Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulat ...

against

rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, ...

on Joseph Meister, a 9-year-old boy who had been mauled by a rabid dog. In 1887 at the request of Pasteur, Grancher defended the rabies vaccination to the

Académie de Médecine An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosop ...

, citing its successful survival rate.

References

External links

Portail Institut Pasteur
(chronological biography) {{DEFAULTSORT:Grancher, Jacques-Joseph 1843 births 1907 deaths People from Creuse French pediatricians Burials at Montmartre Cemetery