Teva api is an international

pharmaceutical company The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate sympto ...

headquartered in

Israel Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated ...

. teva api is a stand-alone business unit of Teva Pharmaceutical Industries limited, the largest generic drug manufacturer in the world and one of the 15 largest pharmaceutical companies worldwide. On top of supplying a major share of Teva's own needs, the Teva api division is an active competitor in world markets, investing both in the development of new products and manufacturing processes and in the upgrading of production facilities. In 2014, Teva api's sales to third parties totaled $724 million. In recent years growth occurred in all of Teva api's principal geographical markets: North America,

Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a subcontinent of Eurasia and it is located entirel ...

and International. As of 2013, teva api employs over 5,000 professionals worldwide, and offers a rich portfolio of about 400

active pharmaceutical ingredient An active ingredient is any ingredient that provides biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals. The ...

History

At the heart of the API division is the Israel-based Teva-Tech, formerly known as the Assia and Plantex plants which manufacture, develop and market raw materials for pharmaceuticals.

Acquisitions

Teva api has grown by acquiring top rated manufacturing and development facilities around the world. Today, teva api operates 21 plants and sales offices worldwide. Major Teva api's acquisitions: *2011 - Teva Acquisition of

Theramex Theramex is a pharmaceutical company based in London which produces women's health products focusing on contraception, fertility, menopause and osteoporosis. It was established in 2018 with the acquisition of some of the assets of Teva Active Ph ...

in Monaco * Teva api 2008 Acquisitions ** December 2008 – Teva Acquisition of

Barr Barr may refer to: Places * Barr (placename element), element of place names meaning 'wooded hill', 'natural barrier' * Barr, Ayrshire, a village in Scotland * Barr Building (Washington, DC), listed on the US National Register of Historic Places ...

Pliva Pliva d.o.o. is a pharmaceutical company based in Zagreb, Croatia that primarily manufactures and sells generic drugs. It is a subsidiary of Teva Pharmaceuticals. Pliva is one of the world's largest producers of Generic drug, generic Adderall. ...

in Croatia ** July 2008 – Teva Acquisition of Bentley in Spain ** April 2008 – Teva api Acquisition of Archimica in Puerto Rico * Acquisitions & Foundations since the 1990s ** 2006 – Acquisition of Wanma in China ** 2006 – Acquisition of Ivax Corporation ** 2004 – Acquisition of Sicor API in Italy, Mexico and Switzerland ** 2003 – Acquisition of RDL in India ** 2002 – Acquisition of PFC in Italy ** 1996 – Acquisition of BIOCRAFT in Missouri (US) ** 1995 – Foundation of TEVA-TECH in Israel ** 1995 – Acquisition of ICI in Italy & BIOGAL in Hungary ** 1991 – Acquisition of PROSINTEX in Italy

Facilities

Research and development

The R&D group at teva api consists of a team of over 760 top scientists located in 7 development centers worldwide: A large center in

(synthetic products and

peptide Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. ...

s), a large center in

Hungary Hungary ( hu, Magyarország ) is a landlocked country in Central Europe. Spanning of the Pannonian Basin, Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the ...

( fermentation and semi-synthetic products), and a facility in

India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...

and additional sites in

Italy Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical ...

Croatia , image_flag = Flag of Croatia.svg , image_coat = Coat of arms of Croatia.svg , anthem = "Lijepa naša domovino"("Our Beautiful Homeland") , image_map = , map_caption = , capit ...

Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...

and the

Czech Republic The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The ...

(development of high potency API). teva api's R&D focuses on the development of processes for the manufacturing of API, including intermediates, chemical and biological (fermentation), which are of interest to the generic drug industry, as well as Teva's proprietary drugs. The API R&D division also seeks methods to continuously reduce API production costs, enabling teva api to improve its cost structure.

Manufacturing and technology

Teva has 15 API production facilities located in Israel, Hungary, Italy, the U.S., the Czech Republic, India, Mexico, Puerto Rico, Monaco, China and Croatia. TAPI's holds expertise in a variety of production technologies, including

chemical synthesis As a topic of chemistry, chemical synthesis (or combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In mod ...

semi-synthetic Semisynthesis, or partial chemical synthesis, is a type of chemical synthesis that uses chemical compounds isolated from natural sources (such as microbial cell cultures or plant material) as the starting materials to produce novel compounds with ...

fermentation,

enzymatic Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. ...

synthesis, high Potency (pharmacology), potent manufacturing, Herbalism, plant extract technology, synthetic peptides, vitamin D derivatives and prostaglandins. Also, its advanced technology and expertise in the field of solid state particle technology enables it to meet specifications for particle size distribution (PSD), bulk density, specific surface area, Polymorphism (materials science), polymorphism, as well as other characteristics. Teva's API facilities meet all applicable current Good manufacturing practice, Good Manufacturing Practices (cGMP) requirements under U.S., European, Japanese, and other applicable quality standards. In some of the products that are sold in the U.S., TAPI utilizes controlled substances and therefore must meet the requirements of the Controlled Substances Act and the related regulations administered by the Drug Enforcement Administration.

Products

Teva api produces approximately 400

s covering a wide range of products, including Respiratory system, respiratory, cardiovascular, anti-cholesterol, central nervous system, Dermatology, dermatological, hormones, anti-inflammatory, oncology, Immunosuppressive drug, immunosuppressants and muscle relaxants. Its API intellectual property portfolio includes over 1,200 granted patents and pending applications worldwide.

References

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External links

Teva Active Pharmaceutical Ingredients official website

Teva official website
Pharmaceutical companies of Israel Science and technology in Israel Israeli brands Pharmaceutical companies established in 1935 Life sciences industry Companies based in Petah Tikva