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The 
chemical compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element ...
isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite
In organic chemistry, alkyl nitrites are a group of organic compounds based upon the molecular structure , where R represents an alkyl group. Formally they are alkyl esters of nitrous acid. They are distinct from nitro compounds ().
The first ...
made from isopropanol
Isopropyl alcohol (IUPAC name propan-2-ol and also called isopropanol or 2-propanol) is a colorless, flammable organic compound with a pungent alcoholic odor. As an isopropyl group linked to a hydroxyl group (chemical formula ) it is the sim ...
. It is a clear pale yellow oil that is insoluble in water.
Applications
Isopropyl nitrite is one of the compounds used aspoppers
Popper is a slang term given broadly to drugs of the chemical class called alkyl nitrites that are inhaled. Most widely sold products include the original isoamyl nitrite or isopentyl nitrite, and isopropyl nitrite. Isobutyl nitrite is also w ...
, an inhalant
Inhalants are a broad range of household and industrial chemicals whose volatile vapors or pressurized gases can be concentrated and breathed in via the nose or mouth to produce intoxication, in a manner not intended by the manufacturer. They ...
drug that induces a brief euphoria
Euphoria ( ) is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Certain natural rewards and social activities, such as aerobic exercise, laughter, listening to or making music and d ...
.
Isopropyl nitrite has largely replaced isobutyl nitrite in poppers.
Safety
''For more information, seepoppers
Popper is a slang term given broadly to drugs of the chemical class called alkyl nitrites that are inhaled. Most widely sold products include the original isoamyl nitrite or isopentyl nitrite, and isopropyl nitrite. Isobutyl nitrite is also w ...
''.
Isopropyl nitrite has been associated with eye maculopathy
A maculopathy is any pathological condition of the macula, an area at the centre of the retina that is associated with highly sensitive, accurate vision.
Forms of maculopathies
* Age-Related Macular Degeneration is a degenerative maculopathy ass ...
, visual impairment with central scotoma
A scotoma is an area of partial alteration in the field of vision consisting of a partially diminished or entirely degenerated visual acuity that is surrounded by a field of normal – or relatively well-preserved – vision.
Every normal mam ...
ta, bilateral foveal
The fovea centralis is a small, central pit composed of closely packed cones in the eye. It is located in the center of the macula lutea of the retina.
The fovea is responsible for sharp central vision (also called foveal vision), which is nece ...
yellow spots, and inner segment/outer segment (IS/OS) junction disruption, which may be reversible.
References
{{Nitric oxide signaling Antianginals Antidotes Alkyl nitrites Isopropyl esters