International Society for Computational Biology
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The International Society for Computational Biology (ISCB) is a
scholarly society A learned society (; also learned academy, scholarly society, or academic association) is an organization that exists to promote an academic discipline, profession, or a group of related disciplines such as the arts and science. Membership may ...
for researchers in
computational biology Computational biology refers to the use of data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the ...
and
bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
. The society was founded in 1997 to provide a stable financial home for the
Intelligent Systems for Molecular Biology Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the co ...
(ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards.


Overview

Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing high-quality meetings, publications, and reports on methods and tools; by disseminating key information about bioinformatics resources and relevant news from related fields; and by actively facilitating training, education, employment, career development, and networking. The society also advocates and provides leadership for resources and policies in support of scientific endeavors and to benefit society at large. ISCB seeks to communicate the significance of computational biology to the larger scientific community, to governmental organizations, and to the general public; the society serves its members locally, nationally, and internationally; it provides guidance for scientific policies, publications, meetings, and distributes information through multiple platforms. ISCB organizes the
Intelligent Systems for Molecular Biology Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the co ...
(ISMB) conference every year, a growing number of smaller, more regionally or topically focused annual and bi-annual conferences, and has three official journals: ''ISCB Community Journal,
PLOS Computational Biology ''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computatio ...
'' and ''
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
''. The society awards three scientific achievement awards annually: the Overton Prize, the ISCB Innovator Award, and the ISCB Senior Scientist Awards. The society elects ISCB Fellows annually, to honor members that have distinguished themselves through outstanding contributions to the fields of computational biology and bioinformatics. The ISCB also awards the ISCB Outstanding Contributions Award to recognize members of the community who have significantly contributed to the success of the organization.


History


Founding

The
Intelligent Systems for Molecular Biology Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the co ...
(ISMB) conference series began in 1993. As a response to the expansion of the conference, the ISCB was founded in 1997 with a significant part of its remit being to provide a stable financial home for ISMB. The ISCB was legally incorporated in early 1997, with Lawrence Hunter elected as its inaugural president by the members of the founding board of directors, which included Russ Altman,
Philip Bourne Philip Eric Bourne (born 1953) is an Australian bioinformatician, non-fiction writer, and businessman. He is currently Stephenson Chair of Data Science and Director of the School of Data Science and Professor of Biomedical Engineering and was the ...
, David States and
Alfonso Valencia Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center. and of Spanish National Bioinformatics Institute (INB-ISCIII). From 2015-2018, he was President of the ...
. The ISCB has organized the ISMB conference since 1998. During the next few years the focus remained on management of the annual ISMB conference, whose 1993 attendance of approximately 200 researchers had more than tripled by 1999. The new millennium brought in a new president in Russ Altman, currently chair of Stanford University's department of bioengineering and director of the program in biomedical informatics, and over 1,200 delegates attended ISMB 2000 in
San Diego San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the eighth most populous city in the United States ...
. Altman took steps to formalize some of the legal and administrative aspects of ISCB before passing the torch in 2002 to Philip E. Bourne, currently professor in the department of pharmacology and Skaggs School of Pharmacy and Pharmaceutical Sciences at the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, University of California, Irvine, Irvine, University of Califor ...
,
San Diego San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the eighth most populous city in the United States ...
. Bourne gave ISCB a more permanent home at UCSD, which included the university's commitment to host the society through at least 2005 and its offer of staff support. Although Bourne served as president for only one year, he left his mark on the society by increasing the interaction with regional groups and conference organizers worldwide, and through an improved web presence. During his tenure, membership grew to more than 1,700 researchers, and the 2002 ISMB conference in Edmonton, Alberta, Canada welcomed over 1,600 attendees.


Expansion

Michael Gribskov, then at UCSD's San Diego Supercomputer department and now at the department of biological sciences at
Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and ...
, was elected president in 2003. That year ISMB took place in
Brisbane Brisbane ( ) is the capital and most populous city of the Australian state of Queensland, and the third-most populous city in Australia and Oceania, with a population of approximately 2.6 million. Brisbane lies at the centre of the South ...
, Australia, which was the first time the meeting was held outside North America or Europe. This phase brought many uncertainties for the society when attendance dropped to one half of budgeted expectations due to travel fears and restrictions related to outbreaks of Severe Acute Respiratory Syndrome or
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''seve ...
, the start of the war in Iraq, and the location, which broke with the pattern of North American and European venues. Although scientifically successful, the financial losses of ISMB 2003 left ISCB financially unstable for the first time in its history. In part to reduce ISCB's dependence on ISMB proceeds to fund the society's activities and annual overhead costs, a pilot regional conference was hosted in the US to gauge interest in smaller, localized meetings. In December 2003, the Rocky Mountain Regional Bioinformatics conference, Rocky 1, was launched in
Aspen Aspen is a common name for certain tree species; some, but not all, are classified by botanists in the section ''Populus'', of the '' Populus'' genus. Species These species are called aspens: *'' Populus adenopoda'' – Chinese aspen (C ...
, Colorado. The meeting has been held annually ever since and now attracts attendees from around the world. In 2005, as part of the society's discussions about the role of publications and the society's official journal, accompanied by the advent of open access publishing, the ISCB announced a partnership with the
Public Library of Science PLOS (for Public Library of Science; PLoS until 2012 ) is a nonprofit publisher of open-access journals in science, technology, and medicine and other scientific literature, under an open-content license. It was founded in 2000 and laun ...
and launched a new
open access journal Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre op ...
, ''PLoS Computational Biology''. The journal is intended to emphasize computational methods applied to living systems at all scales, from molecular biology to patient populations and ecosystems, and which offer insight for experimentalists. Past president and past publications committee chair Phil Bourne served as the new publication's editor-in-chief and he remains in that role. The first issue of the new journal coincided with the opening day of ISMB 2005, held in
Detroit Detroit ( , ; , ) is the largest city in the U.S. state of Michigan. It is also the largest U.S. city on the United States–Canada border, and the seat of government of Wayne County. The City of Detroit had a population of 639,111 at t ...
,
Michigan Michigan () is a state in the Great Lakes region of the upper Midwestern United States. With a population of nearly 10.12 million and an area of nearly , Michigan is the 10th-largest state by population, the 11th-largest by area, and t ...
.
Burkhard Rost Burkhard Rost is a scientist leading the Department for Computational Biology & Bioinformatics at the Faculty of Informatics of the Technical University of Munich (TUM). Rost chairs the Study Section Bioinformatics Munich involving the TUM and ...
, then professor in the department of biochemistry and molecular biophysics at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
and now the Alexander von Humboldt Professor and chair of bioinformatics and computational biology, computational sciences at the
Technical University Munich The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Establis ...
, succeeded Michael Gribskov as president in 2007 and has been reelected twice with a current term expiration set for January 2013. Under his tenure the ISMB/ECCB 2007 conference in Vienna, Austria, chaired by
Thomas Lengauer Thomas Lengauer (born 12 November 1952) is a German computer scientist and computational biologist. Education Lengauer studied Mathematics at the Free University of Berlin, earning his Diploma in 1975 and a Dr. rer. nat. (equivalent to a PhD) in 1 ...
of the Max-Planck Institute for Informatics, and co-chaired by
Burkhard Rost Burkhard Rost is a scientist leading the Department for Computational Biology & Bioinformatics at the Faculty of Informatics of the Technical University of Munich (TUM). Rost chairs the Study Section Bioinformatics Munich involving the TUM and ...
and Peter Schuster of the
University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich hi ...
, was further expanded to include a total of eight parallel tracks, and the 2007 conference attendance of approximately 1,700 was back on track with expectations. Vienna as a destination and the Austria Center Vienna were both so well received by the conference organizers and attendees alike that it was selected to host the 2011 conference as well, which is a first for the ISMB series that had never before repeated a location. In 2010 the first ISCB Latin America was held in
Montevideo Montevideo () is the capital and largest city of Uruguay. According to the 2011 census, the city proper has a population of 1,319,108 (about one-third of the country's total population) in an area of . Montevideo is situated on the southern co ...
, Uruguay.


Leadership and Structure

A president, an executive committee, and a
board of directors A board of directors (commonly referred simply as the board) is an executive committee that jointly supervises the activities of an organization, which can be either a for-profit or a nonprofit organization such as a business, nonprofit orga ...
comprise ISCB's scientific leadership, drawing on distinguished, internationally renowned researchers who are elected for their term by the general society membership. The executive director leads the ISCB staff and supports a diverse set of committees dedicated to specific issues that are important to the computational biology and bioinformatics community, including education, policy, and publications.


Presidents


Board of Directors

, notable members of the board of directors include: Alex Bateman, Bonnie Berger, Terry Gaasterland,
Janet Kelso Janet Kelso (born 1975) is a South African computational biologist and Group leader of the Minerva Research Group for Bioinformatics at the Max Planck Institute for Evolutionary Anthropology. She is best known for her work comparing DNA from pre ...
,
Thomas Lengauer Thomas Lengauer (born 12 November 1952) is a German computer scientist and computational biologist. Education Lengauer studied Mathematics at the Free University of Berlin, earning his Diploma in 1975 and a Dr. rer. nat. (equivalent to a PhD) in 1 ...
, Yves Moreau,
Christine Orengo Christine Anne Orengo is a Professor of Bioinformatics at University College London (UCL)Christine Orengo's known for her work on protein structure, particularly the CATH database. Orengo serves as president of the International Society for Co ...
,
Burkhard Rost Burkhard Rost is a scientist leading the Department for Computational Biology & Bioinformatics at the Faculty of Informatics of the Technical University of Munich (TUM). Rost chairs the Study Section Bioinformatics Munich involving the TUM and ...
,
Alfonso Valencia Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center. and of Spanish National Bioinformatics Institute (INB-ISCIII). From 2015-2018, he was President of the ...
and Martin Vingron.


Fellows

The ISCB has elected
Fellows Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses *Fellows Auctioneers, established in 1876. * Fellowes, Inc., manufacturer of wor ...
since 2009. These distinctions are awarded in honour of outstanding contributions to the fields of computational biology and bioinformatics. The inaugural Class was given to previous recipients of the ISCB Accomplishment by a Senior Scientist Award; in following years, the ISCB has sought nominations for Fellows from its members. Fellows are traditionally introduced at the ISCB's flagship
Intelligent Systems for Molecular Biology Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the co ...
conference each year. As of the Class of 2017, 64 Fellows have been elected.


Communities of Special Interest (COSIs)

ISCB Communities of Special Interest (COSIs) are member communities of shared interest that have self-organized and have multiple activities or interactions throughout the year, rather than solely meeting during the SIG program of the ISMB conference. An important goal of any COSI is to foster a topically-focused collaborative community wherein scientists communicate with one another on research problems and/or opportunities in specific areas of computational biology. Such communication is often in the form of meetings, but can also be through other social media tools that allow for vibrant participation in a virtual environment.


Student Council

In 2004, the ISCB Student Council was founded by Manuel Corpas to promote the development of a worldwide community for computational biology students. One of the main roles of the student council is to promote soft skills in order to develop potential in bioinformatics and computational biology trainees. , the student council represents more than 1,000 students worldwide.


Conferences

ISCB grew out of the need for a stable organizational structure to support the planning and manage the finances of the
Intelligent Systems for Molecular Biology Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the co ...
(ISMB) conference series, which had its start in 1993. ISMB is ISCB's most prominent annual activity, toward which a significant portion of resources are dedicated each year. Since 2004, when ISMB is held in Europe, it is held jointly with the European Conference on Computational Biology (ECCB). ISCB began expanding its conference offerings with the introduction of the annual Rocky Mountain Bioinformatics Conference series in 2003, the Conference on Semantics in Healthcare and Life Sciences ( CSHALS) in 2008, the bi-annual ISCB Africa ASBCB Bioinformatics Conference in 2009, and the bi-annual ISCB Latin America Conference in 2010. ISCB also hosts an annual Great Lake Bioinformatics Conference and partners with RECOMB to produce the Regulatory and Systems Genomics Conference with DREAM Challenges. The ISCB-Asia meeting was started in 2012 and continues to take shape after its last conference in 2014 in Japan in conjunction with GIW. In addition to ISCB-organized conferences, the society supports other computational biology and bioinformatics conferences through affiliations and sponsorships. These include the annual
Pacific Symposium on Biocomputing The Pacific Symposium on Biocomputing (PSB) is an annual multidisciplinary scientific meeting co-founded in 1996 by Dr. Teri Klein, Dr. Lawrence Hunter and Sharon Surles. The conference is to presentation and discuss research in the theory and a ...
(PSB), the annual international conference on Research in Computational Molecular Biology (RECOMB), the annual International Conference on Bioinformatics (InCoB), and the annual general meeting of the European Molecular Biology Network or EMBnet.


Official journals

* In 1998 ''
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
'' became the official journal of the ISCB. Dues-paying members of the society benefited from an online subscription to the journal. ISMB conference proceedings have been published in ''Bioinformatics'' since 2001. In 2004, as many ISCB members had institutional subscriptions to ''Bioinformatics'', ISCB decided not to renew its contract with the journal. In January 2009 ''Bioinformatics'' again became an official journal of the ISCB, alongside ''PLOS Computational Biology''. * ''
PLOS Computational Biology ''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computatio ...
'' is an open-access, peer-reviewed journal published monthly by the
Public Library of Science PLOS (for Public Library of Science; PLoS until 2012 ) is a nonprofit publisher of open-access journals in science, technology, and medicine and other scientific literature, under an open-content license. It was founded in 2000 and laun ...
(PLOS). It became an official journal of ISCB in 2005. * In 2015, ISCB announced the formation of the ''ISCB Community Journal'', a dedicated channel on the ''
F1000Research F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than b ...
'' online publishing platform, providing members the opportunity to openly publish research articles regardless of their format or perceived impact.


Affiliated organizations

The ISCB has several affiliated organizations (mainly regional), including the European Molecular Biology Network (EMBnet), the Netherlands Bioinformatics Centre (NBIC), the African Society for Bioinformatics and Computational Biology and the Japanese Society for Bioinformatics. The ISCB is also a founding member of Global Organisation for Bioinformatics Learning, Education and Training (GOBLET). In collaboration with GOBLET, the ISCB is involved in developing core competencies for different types of bioinformatics trainees; these competencies are being used in the development of new bioinformatics curricula.


References

{{DEFAULTSORT:International Society For Computational Biology Computational biology Biology societies Bioinformatics organizations