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The International Life Sciences Institute (ILSI) is a global nonprofit 501(c)(3) organization headquartered in Washington, DC, United States that publishes peer-reviewed studies on nutrition and food safety. It was founded in 1978 by Alex Malaspina, a former
Coca-Cola Coca-Cola, or Coke, is a carbonated soft drink manufactured by the Coca-Cola Company. Originally marketed as a temperance drink and intended as a patent medicine, it was invented in the late 19th century by John Stith Pemberton in Atlant ...
executive (who was affiliated with ILSI until 2001), and it is partially financed by its 300+ members, which includes food and chemical corporations like
BASF BASF SE () is a German multinational chemical company and the largest chemical producer in the world. Its headquarters is located in Ludwigshafen, Germany. The BASF Group comprises subsidiaries and joint ventures in more than 80 countries ...
, McDonald’s, Syngenta and
Pepsi Pepsi is a carbonated soft drink manufactured by PepsiCo. Originally created and developed in 1893 by Caleb Bradham and introduced as Brad's Drink, it was renamed as Pepsi-Cola in 1898, and then shortened to Pepsi in 1961. History Pepsi wa ...
. In 2020, the organization's revenue was $10.1 million.


Structure

Until 2018, ILSI operated as a member organization, whose members were exclusively food and beverage, agricultural, chemical, and pharmaceutical companies. In November 2018, ILSI restructured as a global federation of entities, consisting of non-profit organizations with public and private sector members. Based on its 2020 annual report, 70.8% of its revenue comes from membership dues and committee assessments; 19.2% from grants and contributions; and the remaining from publications and conference registration. According to ILSI’s
bylaws A by-law (bye-law, by(e)law, by(e) law), or as it is most commonly known in the United States bylaws, is a set of rules or law established by an organization or community so as to regulate itself, as allowed or provided for by some higher authorit ...
, at least 51% of its Board of Trustees must come from the
public sector The public sector, also called the state sector, is the part of the economy composed of both public services and public enterprises. Public sectors include the public goods and governmental services such as the military, law enforcement, inf ...
(i.e. academic, government and non-governmental organization representatives). The remainder of the Board is elected from its member companies. According to ILSI, the organization receives in-kind support of time and expertise from volunteer academic, government, and non-governmental scientists.


History

ILSI was formed in 1978 by Alex Malaspina, who was concurrently a senior vice president at Coca-Cola from 1969 until leaving both Coca-Cola and the institute in 2001. In 1986, ILSI employee Michael Gough published a book about Dioxin and Agent Orange entitled ''Dioxin, Agent Orange: The Facts''. The ''
Los Angeles Times The ''Los Angeles Times'' (abbreviated as ''LA Times'') is a daily newspaper that started publishing in Los Angeles in 1881. Based in the LA-adjacent suburb of El Segundo since 2018, it is the sixth-largest newspaper by circulation in the U ...
'' said that ''The Facts'' had "minimal scientific merit" as the book is about "
toxicology Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating e ...
,
teratology Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology. The relate ...
,
carcinogenesis Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abno ...
,
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evide ...
and medicine"—areas where Gough had no authority as his qualifications were in
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
. ''The Times'' said that ''The Facts'' would however be useful to "dioxin defense attorneys, his current employers at the Risk Science Institute of the International Life Sciences Institute in Washington (a chemical industry think tank), and also his future industrial clients." in 2009, partly in response to questions about the neutrality of its science, ILSI published an article “Funding Food Science and Nutrition Research: Financial Conflicts and Scientific Integrity” in ''
The American Journal of Clinical Nutrition ''The American Journal of Clinical Nutrition'' (''AJCN'') is a monthly peer-reviewed biomedical journal in the fields of dietetics and clinical nutrition. The journal was established in 1952 as the ''Journal of Clinical Nutrition'', edited by ...
'', proposing eight conflict-of-interest guidelines regarding industry funding "to protect the integrity and credibility of the scientific record, particularly with respect to health, nutrition and food-safety science". In 2015, ILSI Mexico's operations were suspended for a year by the Board Executive Committee when it was discovered ILSI Mexico had sponsored a local conference where soft drink taxation was discussed, which was viewed as a "public relations effort to influence policy for commercial purposes" by the institute. ILSI Mexico was shut down in 2020. In 2018,
Mars Inc Mars, Incorporated is an American multinational manufacturer of confectionery, pet food, and other food products and a provider of animal care services, with US$40 billion in annual sales in 2021. Mars was ranked as the fourth-largest priva ...
ended their membership in ILSI, and in 2021, Coca-Cola Co. also withdrew from membership. Later that year, ILSI North America rebranded as the “Institute for the Advancement of Food and Nutrition Sciences” (IAFNS). ILSI Global was awarded
Guidestar Candid is an information service specializing in reporting on U.S. nonprofit companies. In 2016, its database provided information on 2.5 million organizations.Wyland, Michael. "GuideStar Introduces Program Metrics Section for Nonprofit Profile ...
's Gold Seal of Transparency in 2021. ILSI Europe is included in European Union's
Transparency Register Lobbying in the European Union, also referred to officially as European interest representation, is the activity of representatives of diverse interest groups or lobbies who attempt to influence the executive and legislative authorities of the E ...
. ILSI Mesoamerica is certified by the Costa Rican government as an organization of public interest.


Controversies


Tobacco industry

In 2001, an editorial in the '' British Medical Journal'' wrote that ILSI received money from
tobacco industry The tobacco industry comprises those persons and companies who are engaged in the growth, preparation for sale, shipment, advertisement, and distribution of tobacco and tobacco-related products. It is a global industry; tobacco can grow in any ...
from 1983 to 1998. ILSI denies accusations that it has ever sought to undermine
tobacco control Tobacco control is a field of international public health science, policy and practice dedicated to addressing tobacco use and thereby reducing the morbidity and mortality it causes. Since most cigarettes and cigars and hookahs contain/use ...
efforts. In a Letter to the ''
American Journal of Public Health The ''American Journal of Public Health'' is a monthly peer-reviewed public health journal published by the American Public Health Association that covers health policy and public health. The journal was established in 1911 and its stated miss ...
'', ILSI responded to these allegations by saying that there is “little question that the tobacco industry has engaged in a variety of tactics to thwart public health efforts… As a scientific organization, ILSI deplores these tactics and is strongly against any attempts to twist and manipulate science.” As of 2019, ILSI entities are prohibited from accepting as members or accepting funds from tobacco companies. A 2019 New York Times article described ILSI as an organization 'which championed tobacco interests during the 1980s and 1990s.'


Nutrition

Nutritionist Barry Popkin says that in China ILSI had “an extremely harmful influence, because they prevented raising awareness for a healthy diet.”Wie Coca-Cola Chinas Gesundheitspolitik manipuliert
Der Standard ''Der Standard'' is an Austrian daily newspaper published in Vienna. History and profile ''Der Standard'' was founded by Oscar Bronner as a financial newspaper and published its first edition on 19 October 1988. German media company Axel Sprin ...
, 13 January 2019.
Susan Greenhalgh
Making China safe for Coke: how Coca-Cola shaped obesity science and policy in China
''
The BMJ ''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Origi ...
'', 9 January 2019.


Sugar industry

In January 2020, an ILSI-sponsored survey report by
Indian Council of Medical Research The Indian Council of Medical Research (ICMR), the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest and largest medical research bodies in the world. The ICMR is funded by the Gove ...
(ICMR) and National Institute of Nutrition (NIN) on consumption of added sugar among Indians, drew criticism from the Alliance Against Conflict of Interest (AACI). They described ILSI as a lobbying arm of food industry, notorious for pursuing policy influence globally, with particular respect to sugary foods and beverages. As such, ILSI was accused of influencing WHO's and Government's decisions in their favour. The AACI “wonder what strategic direction ICMR-NIN, the premier research agency of India, is giving to the people of India when this survey’s findings projected in the media may potentially perpetuate more sugar consumption while pretending to be concerned about non-communicable diseases”.


Notes and references


External links


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{{Authority control Organizations established in 1978 Agricultural organizations based in the United States Food technology organizations Food safety organizations International scientific organizations 1978 establishments in the United States 501(c)(3) organizations Research institutes in Washington, D.C.