The Integrated Microbial Genomes
IMG system is a genome browsing and annotation platform developed by the U.S.
Department of Energy (DOE)-
Joint Genome Institute.
IMG contains all the draft and complete microbial genomes sequenced by the DOE-JGI integrated with other publicly available genomes (including Archaea, Bacteria, Eukarya, Viruses and Plasmids). IMG provides users a set of tools for comparative analysis of microbial genomes along three dimensions: genes, genomes and functions. Users can select and transfer them in the comparative analysis carts based upon a variety of criteria. IMG also includes a genome annotation pipeline that integrates information from several tools, including
KEGG,
Pfam
Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The most recent version, Pfam 35.0, was released in November 2021 and contains 19,632 families.
Uses ...
,
InterPro, and the
Gene Ontology, among others. Users can also type or upload their own gene annotations (called MyIMG gene annotations) and the IMG system will allow them to generate
Genbank or
EMBL
The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and ...
format files containing these annotations.
In successive releases IMG has expanded to include several domain-specific tools. The Integrated Microbial Genomes with Microbiome Samples''
(IMG/M)system is an extension of the IMG system providing a comparative analysis context of assembled
metagenomic data with the publicly available isolate genomes.
The Integrated Microbial Genomes- Expert Review''
(IMG/ER)system provides support to individual scientists or group of scientists for functional annotation and curation of their microbial genomes of interest.
Users can submit their annotated genomes (or request the IMG automated annotation pipeline to be applied first) into IMG-ER and proceed with manual curation and comparative analysis in the system, through secure (password protected) access. The IMG-HMP is focused on analysis of genomes related to the
Human Microbiome Project (HMP) in the context of all publicly available genomes in IMG. The '
IMG-ABC'' system is a system for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery. The '
IMG-VR'' system (with the recent updated version IMG/VR v.2.0) is the largest publicly available database for viral genomes and metagenomes.
See also
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Genomes OnLine Database
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
*
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental or clinical samples by a method called sequencing. The broad field may also be referred to as environmental genomics, ecogenomics, community genomics or microb ...
*
MicrobesOnline
References
External links
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IMG/M home pageMicrobesOnlineNCBI Microbial GenomesTIGR Comprehensive Microbial ResourceThe SEED
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Biological databases
Pathogen genomics