Influenza A virus subtype H7N2
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Influenza A virus subtype H7N2 (A/H7N2) is a subtype of the species Influenza A virus. This subtype is one of several sometimes called
bird flu "Bird Flu" is an urumee melam-dance song by recording artist M.I.A. on her second studio album '' Kala'' (2007). It was released as a digital download in 2006 through XL Recordings under exclusive license to Interscope Records in the US. Cr ...
virus. H7N2 is considered a low pathogenicity avian influenza (LPAI) virus. With this in mind, H5 & H7 influenza viruses can re-assort into the Highly Pathogenic variant if conditions are favorable. A
CDC The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
study following outbreaks of H7N2 in commercial poultry farms in western Virginia in 2002 concluded: :An important factor contributing to rapid early spread of AI virus infection among commercial poultry farms during this outbreak was disposal of dead birds via rendering off-farm. Because of the highly infectious nature of AI virus and the devastating economic impact of outbreaks, poultry farmers should consider carcass disposal techniques that do not require off-farm movement, such as burial, composting, or incineration. One person in
Virginia Virginia, officially the Commonwealth of Virginia, is a state in the Mid-Atlantic and Southeastern regions of the United States, between the Atlantic Coast and the Appalachian Mountains. The geography and climate of the Commonwealth ar ...
, United States in 2002, one person in New York, United States, in 2003, and one person in New York, United States, in 2016NYC DOHMH 2016 Health Alert #52: Update on Avian Influenza A H7N2 Infection in Cats in NYC Shelters
/ref> were found to have serologic evidence of infection from H7N2; all fully recovered. An analysis of the New York 2003 case concluded that the H7N2 virus responsible could be evolving toward the same strong sugar-binding properties of the three worldwide viral pandemics in 1918, 1957 and 1968. (
Human flu Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, an ...
s and bird flus differ in the molecules they are good at binding with because mammals and
bird Birds are a group of warm-blooded vertebrates constituting the class Aves (), characterised by feathers, toothless beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart, and a strong yet lightweig ...
s differ in the molecules on the cell surface to be bound with. Humans have very few cells with the bird sugar on its cell surface.) A study with ferrets showed that this H7N2 strain could be passed from mammal to mammal. In February 2004, an outbreak of low pathogenic avian influenza (LPAI) A (H7N2) was reported on 2 chicken farms in
Delaware Delaware ( ) is a state in the Mid-Atlantic region of the United States, bordering Maryland to its south and west; Pennsylvania to its north; and New Jersey and the Atlantic Ocean to its east. The state takes its name from the adjacent Del ...
and in four live bird markets in
New Jersey New Jersey is a state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north and east by the state of New York; on the east, southeast, and south by the Atlantic Ocean; on the west by the Delaware ...
supplied by the same farms. In March 2004, surveillance samples from a flock of chickens in
Maryland Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to ...
tested positive for LPAI H7N2. It is likely that this was the same strain. On 24 May 2007, an outbreak of H7N2 was confirmed at a poultry farm near
Corwen Corwen is a town and community in the county of Denbighshire in Wales. Historically, Corwen is part of the county of Merionethshire. Corwen stands on the banks of the River Dee beneath the Berwyn mountains. The town is situated west of Llango ...
, in
Wales Wales ( cy, Cymru ) is a country that is part of the United Kingdom. It is bordered by England to the east, the Irish Sea to the north and west, the Celtic Sea to the south west and the Bristol Channel to the south. It had a population in ...
from tests on chickens that died from H7N2. The owners of the Conwy farm bought 15
Rhode Island Red The Rhode Island Red is an American breed of domestic chicken. It is the state bird of Rhode Island. It was developed there and in Massachusetts in the late nineteenth century, by cross-breeding birds of Oriental origin such as the Malay wit ...
chickens two weeks prior but all died from H7N2. The 32 other poultry at the site were slaughtered. A one kilometer exclusion zone was put in force around the property in which birds and bird products cannot be moved and bird gathering can only take place under licence. Nine people who were associated with the infected or dead poultry and reported flu-like symptoms were tested. Four tested positive for evidence of infection from H7N2 and were successfully treated for mild flu. In early June it was discovered that the virus had spread to a poultry farm 70 miles (113 km) away near St. Helens in north-west England. All the poultry at the farm were slaughtered and a 1 km exclusion zone imposed. In December 2016, an outbreak of low pathogenic avian influenza H7N2 occurred in a feline population in the New York City Animal Care Center (ACC) shelters after testing by the University of Wisconsin-Madison School of Veterinary Medicine and confirmed by USDA's National Veterinary Diagnostic Services Laboratory.NYC DOHMH 2016 Veterinary Advisory # 1: Influenza A, H7N2 Identified in Cats from Animal Care Centers of New York City Facility in Manhattan
/ref> Over 100 cats were found to be infected and subsequently quarantined, but only one human, a veterinarian involved in obtaining respiratory specimens, was found to be infected. The veterinarian had a brief illness with mild symptoms and recovered completely. All other humans exposed to the infected cats tested negative.


References


Further reading



* [https://web.archive.org/web/20040323154836/http://www.umaine.edu/livestock/NECAD/2002%20Abstracts/DHenzler.doc Epidemiology of an H7N2 Avian Influenza Outbreak in Broilers in Pennsylvania in November 2001– January 2002]
Avian influenza H7N2 in Wales and the Northwest of England

North Wales bird flu outbreak ends


External links


Influenza Research Database
Database of influenza sequences and related information.

{{Taxonbar, from=Q6030290
H7N2 Influenza A virus subtype H7N2 (A/H7N2) is a subtype of the species Influenza A virus. This subtype is one of several sometimes called bird flu virus. H7N2 is considered a low pathogenicity avian influenza (LPAI) virus. With this in mind, H5 & ...