IPlant Collaborative
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The iPlant Collaborative, renamed Cyverse in 2017, is a virtual organization created by a cooperative agreement funded by the US
National Science Foundation The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National ...
(NSF) to create
cyberinfrastructure United States federal research funders use the term cyberinfrastructure to describe research environments that support advanced data acquisition, data storage, data management, data integration, data mining, data visualization and other computing a ...
for the plant sciences (
botany Botany, also called , plant biology or phytology, is the science of plant life and a branch of biology. A botanist, plant scientist or phytologist is a scientist who specialises in this field. The term "botany" comes from the Ancient Greek w ...
). The NSF compared cyberinfrastructure to physical infrastructure, "... the distributed computer, information and communication technologies combined with the personnel and integrating components that provide a long-term platform to empower the modern scientific research endeavor". In September 2013 it was announced that the National Science Foundation had renewed iPlant's funding for a second 5-year term with an expansion of scope to all non-human life science research. The project develops computing systems and software that combine computing resources, like those of
TeraGrid TeraGrid was an e-Science grid computing infrastructure combining resources at eleven partner sites. The project started in 2001 and operated from 2004 through 2011. The TeraGrid integrated high-performance computers, data resources and tools, a ...
, and bioinformatics and computational biology software. Its goal is easier collaboration among researchers with improved data access and processing efficiency. Primarily centered in the United States, it collaborates internationally.


History

Biology is relying more and more on computers. Plant biology is changing with the rise of new technologies. With the advent of bioinformatics, computational biology, DNA sequencing, geographic information systems and others computers can greatly assist researchers who study plant life looking for solutions to challenges in
medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pr ...
, biofuels,
biodiversity Biodiversity or biological diversity is the variety and variability of life on Earth. Biodiversity is a measure of variation at the genetic (''genetic variability''), species (''species diversity''), and ecosystem (''ecosystem diversity'') l ...
,
agriculture Agriculture or farming is the practice of cultivating plants and livestock. Agriculture was the key development in the rise of sedentary human civilization, whereby farming of domesticated species created food surpluses that enabled people t ...
and problems like
drought tolerance Drought tolerance is the ability to which a plant maintains its biomass production during arid or drought conditions. Some plants are naturally adapted to dry conditions'','' surviving with protection mechanisms such as desiccation tolerance, detox ...
, plant breeding, and sustainable farming. Many of these problems cross traditional disciplines and facilitating collaboration between plant scientists of diverse backgrounds and specialties is necessary. In 2006, the NSF solicited proposals to create "a new type of organization – a cyberinfrastructure collaborative for plant science" with a program titled "Plant Science Cyberinfrastructure Collaborative" (PSCIC) with Christopher Greer as program director. A proposal was accepted (adopting the convention of using the word "Collaborative" as a noun) and iPlant was officially created on February 1, 2008. Funding was estimated as $10 million per year over five years. Richard Jorgensen led the team through the proposal stage and was the
principal investigator In many countries, the term principal investigator (PI) refers to the holder of an independent grant and the lead researcher for the grant project, usually in the sciences, such as a laboratory study or a clinical trial. The phrase is also often us ...
(PI) from 2008 to 2009. Gregory Andrews, Vicki Chandler, Sudha Ram and Lincoln Stein served as Co-Principal Investigators (Co-PIs) from 2008 to 2009. In late 2009, Stephen Goff was named PI and Daniel Stanzione was added as a Co-PI. As of May 2014, Co-PI Stanzione was replaced by 4 new Co-PIs: Doreen Ware at Cold Spring Harbor, Nirav Merchant and Eric Lyons at the University of Arizona, and Matthew Vaughn at the Texas Advanced Computing Center. The iPlant project supports what has been called
e-Science E-Science or eScience is computationally intensive science that is carried out in highly distributed network environments, or science that uses immense data sets that require grid computing; the term sometimes includes technologies that enable dist ...
, which is a use of information systems technology that is being adopted by the research community in efforts such as the
National Center for Ecological Analysis and Synthesis The National Center for Ecological Analysis and Synthesis (NCEAS) is a research center at the University of California, Santa Barbara, in Santa Barbara, California. Better known by its acronym, NCEAS (pronounced “n-seas”) opened in May 1995. Fu ...
(NCEAS), ELIXIR, and the Bamboo Technology Project that started in September 2010. iPlant is "designed to create the foundation to support the computational needs of the research community and facilitate progress toward solutions of major problems in plant biology." The project works as a collaboration. It seeks input from the wider plant science community on what to build. Based on that input, it has enabled easier use of large data sets, created a community-driven research environment to share existing data collections within a research area and between research areas and shares data with provenance tracking. One model studied for collaboration was
Wikipedia Wikipedia is a multilingual free online encyclopedia written and maintained by a community of volunteers, known as Wikipedians, through open collaboration and using a wiki-based editing system. Wikipedia is the largest and most-read refer ...
. Several more recent National Science Foundation awards mentioned iPlant explicitly in their descriptions, as either a design pattern to follow or a collaborator with whom the recipient will work.


Institutions

The primary institution for the iPlant project is the
University of Arizona The University of Arizona (Arizona, U of A, UArizona, or UA) is a public land-grant research university in Tucson, Arizona. Founded in 1885 by the 13th Arizona Territorial Legislature, it was the first university in the Arizona Territory. T ...
, located within the BIO5 Institute in
Tucson , "(at the) base of the black ill , nicknames = "The Old Pueblo", "Optics Valley", "America's biggest small town" , image_map = , mapsize = 260px , map_caption = Interactive map ...
. Since its inception in 2008, personnel worked at other institutions including
Cold Spring Harbor Laboratory Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, plant biology, genomics, and quantitative biology. It is one of 68 institutions supported by the Cancer Centers ...
, University of North Carolina, Wilmington, and the
University of Texas at Austin The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas. It was founded in 1883 and is the oldest institution in the University of Texas System. With 40,916 undergraduate students, 11,07 ...
in the
Texas Advanced Computing Center The Texas Advanced Computing Center (TACC) at the University of Texas at Austin, United States, is an advanced computing research center that provides comprehensive advanced computing resources and support services to researchers in Texas and acr ...
.
Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and mone ...
and Arizona State University were part of the original project group. Other collaborating institutions that received support from iPlant for their work on a Grand Challenge in
phylogenetics In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups ...
starting in March 2009 included
Yale University Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United Sta ...
,
University of Florida The University of Florida (Florida or UF) is a public land-grant research university in Gainesville, Florida. It is a senior member of the State University System of Florida, traces its origins to 1853, and has operated continuously on its ...
, and the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universitie ...
. A trait evolution group was led at the
University of Tennessee The University of Tennessee (officially The University of Tennessee, Knoxville; or UT Knoxville; UTK; or UT) is a public land-grant research university in Knoxville, Tennessee. Founded in 1794, two years before Tennessee became the 16th state ...
. A visualization workshop employing iPlant was run by
Virginia Tech Virginia Tech (formally the Virginia Polytechnic Institute and State University and informally VT, or VPI) is a public land-grant research university with its main campus in Blacksburg, Virginia. It also has educational facilities in six re ...
in 2011. The NSF requires that funding subcontracts stay within the United States, but international collaboration started in 2009 with the
Technical University Munich The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Establis ...
and
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park (Toronto), Queen's Park. It was founded by royal charter in 1827 ...
in 2010. East Main Evaluation & Consulting provides external oversight, advice, and assistance.


Services

The iPlant project makes its cyberinfrastructure available several different ways and offers services to make it the accessible to its primary audience. The design was meant to grow in response to needs of the research community it serves.


The Discovery Environment

The Discovery Environment integrates community-recommended software tools into a system that can handle
terabyte The byte is a unit of digital information that most commonly consists of eight bits. Historically, the byte was the number of bits used to encode a single character of text in a computer and for this reason it is the smallest addressable uni ...
s of data using high-performance supercomputers to perform these tasks much more quickly. It has an interface designed to hide the complexity needed to do this from the end user. The goal was to make the cyberinfrastructure available to non-technical end users who are not as comfortable using a command-line interface.


iPlant Foundational APIs

A set of application programming interfaces (APIs) for developers allow access to iPlant services, including authentication, data management, high performance supercomputing resources from custom, locally produced software.


Atmosphere

Atmosphere is a
cloud computing Cloud computing is the on-demand availability of computer system resources, especially data storage ( cloud storage) and computing power, without direct active management by the user. Large clouds often have functions distributed over mu ...
platform that provides easy access to pre-configured, frequently used analysis routines, relevant algorithms, and data sets, and accommodates computationally and data-intensive bioinformatics tasks. It uses the
Eucalyptus ''Eucalyptus'' () is a genus of over seven hundred species of flowering trees, shrubs or mallees in the myrtle family, Myrtaceae. Along with several other genera in the tribe Eucalypteae, including '' Corymbia'', they are commonly known as e ...
virtualization platform.


iPlant Semantic Web

The iPlant Semantic Web effort uses an iPlant-created architecture, protocol, and platform called the Simple Semantic Web Architecture and Protocol ( SSWAP) for semantic web linking using a plant science focused
ontology In metaphysics, ontology is the philosophical study of being, as well as related concepts such as existence, becoming, and reality. Ontology addresses questions like how entities are grouped into categories and which of these entities exi ...
. SSWAP is based on the notion of RESTful web services with an ontology based on
Web Ontology Language The Web Ontology Language (OWL) is a family of knowledge representation languages for authoring ontologies. Ontologies are a formal way to describe taxonomies and classification networks, essentially defining the structure of knowledge for vario ...
(OWL).


Taxonomic Name Resolution Service

The Taxonomic Name Resolution Service (TNRS) is a free utility for correcting and standardizing plant names. This is needed because plant names that are misspelled, out of date (because a newer synonym is preferred), or incomplete make it hard to use computers to process large lists.


My-Plant

My-Plant.org is a social networking community for plant biologists, educators and others to come together to share information and research, collaborate, and track the latest developments in plant science. The My-Plant network uses the terminology '' clades'' to group users in a manner similar to
phylogenetics In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups ...
of plants themselves. It was implemented using Drupal as its content management system.


DNA Subway

The DNA Subway website uses a
graphical user interface The GUI ( "UI" by itself is still usually pronounced . or ), graphical user interface, is a form of user interface that allows users to interact with electronic devices through graphical icons and audio indicator such as primary notation, inst ...
(GUI) to generate DNA sequence annotations, explore plant
genome In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding g ...
s for members of gene and
transposon A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Tra ...
families, and conduct
phylogenetic In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups o ...
analyses. It makes high-level DNA analysis available to faculty and students by simplifying annotation and comparative genomics workflows. It was developed for iPlant by the Dolan DNA Learning Center.


References


External links

* ** ** ** {{Cite web , title= Fast Track to Gene Annotation and Genome Analysis - DNA Subway , work= Tool web site , publisher= iPlant Collaborative , url= http://www.dnasubway.org , access-date= September 21, 2011 E-Science Organizations established in 2008