Hutchinson's sign is a clinical sign which may refer to: * Hutchinson's pupil, an unresponsive and enlarged pupil on the side of an intracranial mass * Vesicles on the tip of the nose, or vesicles on the side of the nose, precedes the development of ophthalmic

herpes zoster Shingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. ...

. This occurs because the nasociliary branch of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chew ...

innervates both the

cornea The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical ...

and the lateral dorsum of the nose as well as the tip of the nose. This sign is named after Sir Jonathan Hutchinson. *

Melanonychia Melanonychia is a black or brown pigmentation of the normal nail plate, and may be present as a normal finding on many digits in Afro-Caribbeans, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such local ...

with pigmentation of the proximal nail fold.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. . This is an important sign of subungual melanoma although is not an infallible predictor. Periungual hyperpigmentation occurs in at least one nonmelanoma skin cancer, Bowen's disease of the nail unit. This is a nail fold pigmentation which then widens progressively to produce a triangular pigmented macule with associated nail dystrophy. Hyperpigmentation of the nail bed and matrix may reflect through the "transparent" nailfolds simulating Hutchinson's sign. *

Hutchinson's triad Hutchinson's triad is named after Sir Jonathan Hutchinson (1828–1913). It is a common pattern of presentation for congenital syphilis, and consists of three phenomena: interstitial keratitis, malformed teeth ( Hutchinson incisors and mulberry mo ...

- pattern of presentation of

congenital syphilis Congenital syphilis is syphilis present ''in utero'' and at birth, and occurs when a child is born to a mother with syphilis. Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose, lower extr ...

References

Medical signs Dermatologic signs {{med-sign-stub

See also

References