Human hair growth
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The growth of human hair occurs everywhere on the body except for the soles of the feet, the inside of the mouth, the lips, the backs of the ears, the palms of the hands, some external
genital A sex organ (or reproductive organ) is any part of an animal or plant that is involved in sexual reproduction. The reproductive organs together constitute the reproductive system. In animals, the testis in the male, and the ovary in the female, a ...
areas, the
navel The navel (clinically known as the umbilicus, commonly known as the belly button or tummy button) is a protruding, flat, or hollowed area on the abdomen at the attachment site of the umbilical cord. All placental mammals have a navel, although ...
,
scar A scar (or scar tissue) is an area of fibrous tissue that replaces normal skin after an injury. Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. Thus, scarring is a n ...
tissue, and, apart from
eyelash An eyelash (also called lash) (Latin: ''Cilia'') is one of the hairs that grows at the edge of the eyelids. It grows in one layer on the edge of the upper and lower eyelids. Eyelashes protect the eye from debris, dust, and small particles and p ...
es, the
eyelid An eyelid is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. The human eye ...
s. Hair is a stratified squamous
keratin Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, nails, feathers, ho ...
ized epithelium made of multi-layered flat cells whose rope-like filaments provide structure and strength to the
hair shaft Hair is a protein filament that grows from follicles found in the dermis. Hair is one of the defining characteristics of mammals. The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and fine ...
. The protein called
keratin Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, nails, feathers, ho ...
makes up hair and stimulates hair growth. Hair follows a specific growth cycle with three distinct and concurrent phases: anagen,
catagen The growth of human hair occurs everywhere on the body except for the soles of the feet, the inside of the mouth, the lips, the backs of the ears, the palms of the hands, some external genital areas, the navel, scar tissue, and, apart from eyelas ...
, and
telogen The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
. Each phase has specific characteristics that determine the length of the hair. The body has different types of hair, including
vellus hair Vellus hair is short, thin, light-colored, and barely noticeable hair that develops on most of a human’s body during childhood. Exceptions include the lips, the back of the ear, the palm of the hand, the sole of the foot, some external genital ...
and
androgenic hair Body hair, or androgenic hair, is the terminal hair that develops on the human body during and after puberty. It is differentiated from the head hair and less visible vellus hair, which is much finer and lighter in color. The growth of andr ...
, each with its own type of cellular construction. This varied construction gives the hair unique characteristics, serving specific purposes, mainly warmth (redundant in modern humans) and physical protection. Most humans develop the longest thickest hair on their scalps and (mostly observed in males) faces. This hair will usually grow to several feet before terminating, but many humans develop much longer hair.


Growth cycle

The three stages of hair growth are the anagen,
catagen The growth of human hair occurs everywhere on the body except for the soles of the feet, the inside of the mouth, the lips, the backs of the ears, the palms of the hands, some external genital areas, the navel, scar tissue, and, apart from eyelas ...
, and
telogen The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
phases. Each strand of hair on the human body is at its own stage of development. Once the cycle is complete, it restarts and a new strand of hair begins to form. The growth rate of hair varies from individual to individual depending on their age, genetic predisposition and a number of environmental factors. It is commonly stated that hair grows about 1 cm per month on average; however reality is more complex, since not all hair grows at once. Scalp hair was reported to grow between 0.6 cm and 3.36 cm per month. The growth rate of scalp hair somewhat depends on age (hair tends to grow more slowly with age), sex, and ethnicity. Thicker hair (>60 µm) grows generally faster (11.4 mm per month) than thinner (20-30 µm) hair (7.6 mm per month). It was previously thought that Caucasian hair grew more quickly than Asian hair and that the growth rate of women's hair was faster than that of men. However, more recent research has shown that the growth rate of hair in men and women does not significantly differ and that the hair of Chinese people grew more quickly than the hair of French Caucasians and West and Central Africans. The quantity of hair hovers in a certain range depending on hair colour. An average
blonde Blond (male) or blonde (female), also referred to as fair hair, is a hair color characterized by low levels of the dark pigment eumelanin. The resultant visible hue depends on various factors, but always has some yellowish color. The color can ...
person has 150,000 hairs, a
brunette Brown hair, also referred to as brunet (male) or brunette (female), is the second most common human hair color, after black hair. It varies from light brown to a medium dark hair. It is characterized by higher levels of the dark pigment eume ...
has 110,000, a black-haired person has 100,000, and a
redhead Red hair (also known as orange hair and ginger hair) is a hair color found in one to two percent of the human population, appearing with greater frequency (two to six percent) among people of Northern or Northwestern European ancestry and ...
has 90,000. Hair growth stops after a human's death. Visible growth of hair on the dead body happens only because of skin drying out due to water loss.


Anagen phase

The anagen phase, known as the growth phase, is when the hair physically grows approximately 1 cm per month. It begins in the
papilla Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of ...
and can last from three to five years. The span at which the hair remains in this stage of growth is determined by genetics. The longer the hair stays in the anagen phase, the longer it will grow. During this phase, cells neighboring the
papilla Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of ...
in a germinative layer divide to produce new hair fibers, and the follicle buries itself into the
dermal The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain. It is divided ...
layer of the skin to nourish the strand. About 85%–90% of the hairs on one's head are in the anagen phase at any given time.


Catagen phase

The catagen phase, or the transitional phase, allows the follicle to renew itself (in a sense). During this time, which lasts about two weeks, the hair follicle shrinks due to disintegration and the papilla detaches and "rests," cutting the hair strand off from its nourishing blood supply. Signals sent out by the body (that only selectively affect 1 percent of all hair of one's body at any given time) determine the end of melanin production in the hair bulb and apoptosis of follicular melanocytes. Ultimately, the follicle is 1/6 its original length, causing the hair shaft to be pushed upward.


Growth inhibitors and disorders

In most people, scalp hair growth will halt due to follicle devitalization after reaching a length of generally two or three feet. Exceptions to this rule can be observed in individuals with hair development abnormalities, which may cause an unusual length of hair growth.


Chemotherapy

Most
chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs ( chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemothe ...
drugs work by attacking rapidly dividing cells. Rapid cell replication is one of the hallmarks of cancer; however, hair follicle cells also grow and divide quickly. Consequently, the chemotherapy drugs usually inhibit hair growth. The dose and type of medicine will determine the severity of hair loss. Once the course of chemotherapy has ended, new hair growth may begin after three to 10 weeks.


Hair loss

Alopecia Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body. Typically at least the head is involved. The severity of hair loss can vary from a small area to the entire body. Inflammation or scar ...
is a hair loss disease that can occur in anyone at any stage of life. Specifically
alopecia areata Alopecia areata, also known as spot baldness, is a condition in which hair is lost from some or all areas of the body. Often, it results in a few bald spots on the scalp, each about the size of a coin. Psychological stress and illness are pos ...
is an autoimmune disease that causes hair to spontaneously fall out. It is mainly characterized by bald patches on the scalp or other parts of the body, and can ultimately cause baldness across the entire body. This disease interferes with the hair growth cycle by causing a follicle to prematurely leave the anagen, or active growth, phase and enter the resting, or
telogen The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
, phase. The hair growth in the affected follicles is lessened or stopped completely.
Traction alopecia Traction alopecia is a type of alopecia or hair loss caused by a chronic pulling force being applied to the hair. It commonly results from a person frequently wearing their hair in a particularly tight ponytail, pigtails, or braids with increased ...
is caused by adding too much strain on the hair on one's head. Tight ponytails and other styles that require added tension to the hair are often what cause this disease. It can also occur on the face in areas where the hair is often styled. Plucking or waxing one's eyebrows frequently, for example, can yield suppressed hair growth in the area. On the scalp, the hair is usually known to be lost around the hair line, leaving the densest amount of hair at the crown. Small
vellus hair Vellus hair is short, thin, light-colored, and barely noticeable hair that develops on most of a human’s body during childhood. Exceptions include the lips, the back of the ear, the palm of the hand, the sole of the foot, some external genital ...
will often replace the hair that is lost.


Radiation therapy to the head

Human hair follicles are very sensitive to the effects of
radiation therapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radi ...
administered to the head, most commonly used to treat cancerous growths within the brain. Hair shedding may start as soon as two weeks after the first dose of radiation and will continue for a couple of weeks. Hair follicles typically enter the
telogen The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
phase, and regrowth should commence 2.5 to 3 months after the hair begins to shed. Regrowth may be sparser after treatment.


UV-B

Ultraviolet light levels of either 20 or 50 mJ cm−2 in the
UV-B Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nm (with a corresponding frequency around 30  PHz) to 400 nm (750  THz), shorter than that of visible light, but longer than X-rays. UV radiation i ...
range have been shown to inhibit hair growth, reduce hair
melanin Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino ...
and damage hair follicles.


See also

* Evolution of hair *
Hair transplantation Hair transplantation is a surgical technique that removes hair follicles from one part of the body, called the 'donor site', to a bald or balding part of the body known as the 'recipient site'. The technique is primarily used to treat male patt ...


References

{{Human hair Human hair