Homeobox protein Hox-B1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''HOXB1''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
Interactions
HOXB1 has been shown to
interact with
PBX1
Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the ''PBX1'' gene.
Interactions
PBX1 has been shown to Protein-protein interaction, interact with:
* HOXB1,
* HOXB7,
* MEIS1, and
* PKNOX1, Prep1.
Referen ...
.
See also
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Homeobox
References
Further reading
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External links
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Transcription factors
{{gene-17-stub