Hepatic fructokinase (or ketohexokinase) is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...

that catalyzes the phosphorylation of fructose to produce

fructose-1-phosphate Fructose-1-phosphate is a derivative of fructose. It is generated mainly by hepatic fructokinase but is also generated in smaller amounts in the small intestinal mucosa and proximal epithelium of the renal tubule. It is an important intermediate o ...

. :ATP +

\longrightarrow

ADP +

: ATP + D-fructose → ADP + D-fructose-1-phosphate

Pathology

A deficiency is associated with essential fructosuria.

References

External links

* EC 2.7.1 {{2.7-enzyme-stub