The ham sandwich is one of the earliest recorded closed-face sandwiches; by 1850, at least 70 London street vendors offered it. In 18th-century Britain the sandwich was still closely associated with Spanish cuisine, which (considering the especially wide consumption of ham in Spain) may suggest that sandwiches with ham were preferred at that time as well. There were also records of closed face sandwiches on Melrose St. In Providence RI in the 1850s
The British Sandwich Association says that the ham sandwich is the most popular sandwich in the UK, and a survey they conducted in 2001 saw ham as the second favourite filling behind cheese. 70% of the 1.8 billion sandwiches eaten in France in 2008 were ham sandwiches, prompting a French economic analysis firm to begin a 'jambon-beurre index', like the Big Mac Index, to compare prices across the country.
The world's longest ham sandwich was created by butcher Nico Jimenez in Pamplona, Spain in 2009.
A fictional talking ham sandwich appeared in an online noir serial in the late 1990s, and the publishers sued in 1999 when a similar character appeared in a television advertisement for Florida orange juice, though the suit was withdrawn.
Before her autopsy revealed a heart attack, it was thought that Mama Cass died from choking on a ham sandwich, as she was lying on the couch with food on the table when she was found dead.