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NM_002145

NM_134032

RefSeq (protein)

NP_002136

NP_598793

Location (UCSC) Chr 17: 48.54 – 48.54 Mb Chr 11: 96.35 – 96.35 Mb PubMed search [3] [4] Wikidata
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Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[5][6][7]

Function

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[7]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173917 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075588 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  6. ^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 
  7. ^ a b "Entrez Gene: HOXB2 homeobox B2". 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.