George Perry (born April 12, 1953) is a professor of biology and chemistry at the

University of Texas at San Antonio The University of Texas at San Antonio (UTSA) is a Public university, public research university in San Antonio, Texas. With over 34,000 students across its four campuses spanning 758 acres, UTSA is the Education in San Antonio, largest universi ...

and the former

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of the College of Sciences. Perry is recognized in the field of Alzheimer's disease research, particularly for his work on

oxidative stress Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal ...

Education

Perry received his Bachelor of Arts degree in zoology from

University of California, Santa Barbara The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a public land-grant research university in Santa Barbara, California with 23,196 undergraduates and 2,983 graduate students enrolled in 2021–2022. It is part of the U ...

. After graduation, he studied at Scripps Institution of Oceanography,

Hopkins Marine Station Hopkins Marine Station is the marine laboratory of Stanford University. It is located ninety miles south of the university's main campus, in Pacific Grove, California (United States) on the Monterey Peninsula, adjacent to the Monterey Bay Aquarium. ...

of Stanford University, and the

Marine Biological Laboratory The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent ...

at Woods Hole; he obtained his Ph.D. from the University of California at San Diego in Marine Biology under

David Epel David Epel is a researcher at Hopkins Marine Station in Pacific Grove, California, and a Professor (Emeritus) in the Department of Biology at Stanford University. Epel earned his Ph.D. at University of California Berkeley under Daniel Mazia. He a ...

in 1979. He then received a postdoctoral fellowship in the Department of Cell Biology in the laboratories of William R. Brinkley, Joseph Bryan and Anthony R. Means at

Baylor College of Medicine Baylor College of Medicine (BCM) is a medical school and research center in Houston, Texas, within the Texas Medical Center, the world's largest medical center. BCM is composed of four academic components: the School of Medicine, the Graduate S ...

where he laid the foundation for his observations of cytoskeletal abnormalities.

Professional appointments

In 1982, Perry joined the faculty of Case Western Reserve University, where he holds an adjunct appointment. He is dean of the College of Sciences and professor of biology at the University of Texas at San Antonio. He is distinguished as one of the top Alzheimer's disease researchers with over 1000 publications, one of the top 100 most-cited scientists in Neuroscience & Behavior and one of the top 25 scientists in free radical research. Perry is highly cited (over 82,500 times;H=137;ISI/over 117,000 times;H=170;Google Scholar) and is recognized as an ISI highly cited researcher. Perry is the current and founding

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ...

for the '' Journal of Alzheimer's Disease'', an international multidisciplinary journal that specialises in Alzheimer's disease. He is also a member of the

Alzheimer's Foundation of America The Alzheimer's Foundation of America (AFA) is an American nonprofit organization based in New York City whose mission is to provide support, services and education to individuals, families and caregivers affected by Alzheimer's disease and relat ...

Medical, Scientific, and Memory Screening Advisory Board. Perry is fellow of the

American Association for the Advancement of Sciences The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsi ...

Sigma Xi Sigma Xi, The Scientific Research Honor Society () is a highly prestigious, non-profit honor society for scientists and engineers. Sigma Xi was founded at Cornell University by a junior faculty member and a small group of graduate students in 1886 ...

, Microscopy Society of America, International Engineering and Technology Institute (IETI), Texas Academy of Sciences, past president and past-interim executive director of the Southwestern and Rocky Mountain Division of American Association for the Advancement of Sciences, past chair of the board of the National Organization of Portuguese Americans and past president of the American Association of Neuropathologists.

Research focus

Perry's research is primarily focused on the mechanism of formation and physiological consequences of the cytopathology of

Alzheimer disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...

. He has played a key role in elucidating oxidative damage as the initial cytopathological abnormality in

. He is currently working to determine the sequence of events leading to neuronal oxidative damage and the source of the increased

oxygen radicals In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron. With some exceptions, these unpaired electrons make radicals highly chemically reactive. Many radicals spon ...

. His current studies focus on two issues: (i) the metabolic basis for the mitochondrial damage restricted to vulnerable neurons; and (ii) the consequences of RNA oxidation on protein synthesis rate and fidelity.

References

External links

Future Neurology Interview

Journal of Alzheimer's Disease

*
Science Watch Top 20 Alzheimer's Researchers

PBS Interview

Express-News Article
{{DEFAULTSORT:Perry, George Alzheimer's disease researchers American neuroscientists Fellows of the American Association for the Advancement of Science Fellows of the Linnean Society of London Living people American people of Portuguese descent University of Texas at San Antonio faculty Allan Hancock College alumni University of California, Santa Barbara alumni People from Lompoc, California 1953 births Scripps Institution of Oceanography alumni