Geoffrey M. Cooper is professor of biology at

Boston University Boston University (BU) is a Private university, private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with ...

. He served as chair of the department of biology for a number of years, and subsequently as associate dean of the faculty for the natural sciences in the university's college of arts & sciences. Cooper earned his Ph.D. at the

University of Miami The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, i ...

in 1973, and was a postdoctoral fellow with nobel laureate,

Howard Temin Howard Martin Temin (December 10, 1934 – February 9, 1994) was an American geneticist and virologist. He discovered reverse transcriptase in the 1970s at the University of Wisconsin–Madison, for which he shared the 1975 Nobel Prize in Phy ...

. His work includes cellular growth control,

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

, and signal transduction. More specifically, he focuses on "the roles of proto-oncogene proteins as elements of signal transduction pathways that control proliferation, differentiation, and survival of mammalian cells." He is also the author of the textbook "The Cell". Cooper’s first novel, a medical thriller titled “The Prize”, was published in January 2018.

Publications

* Terragni J*, Graham JR*, Adams KW, Schaffer ME, Tullai JW, Cooper GM. 2008. Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors. BMC Cell Biol. Jan 28;9:6 *Adams, K.W., and Cooper, G.M. 2007. Rapid turnover of Mcl-1 couples translation to cell survival and apoptosis. J. Biol. Chem. 282:6192-6200. *Tullai, J.W., Chen, J., Schaffer, M.E., Kamenetsky, E., Kasif, S. and Cooper, G.M. 2007. GSK-3b mediates repression of CREB target genes in quiescent cells. J. Biol. Chem. 282:9482-9491. *Tullai, J.W., Schaffer, M.E., Mullenbrock, S., Kasif, S., and Cooper, G.M. 2004. Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways. J. Biol. Chem. 279: 20167-20177. *Pagon, Z., Volker, J., Cooper, G.M., and Hansen, U. 2003. Mammalian transcription factor LSF is a target of ERK signaling. J. Cell. Biochem. 89:733-746. *Hartley, D. and Cooper, G.M. 2002. The role of mTOR in the degradation of IRS-1: regulation of PP2A activity. J. Cell. Biochem. 85:304-314. *Pap, M., and Cooper, G.M. 2002. Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3b pathway. Mol. Cell. Biol. 22:578-586. *Hartley, D. and Cooper, G.M. 2000. Direct binding and activation of STAT transcription factors by the herpesvirus saimiri protein Tip. J. Biol. Chem. 275:16925-16932. *Lin, H., Jurk, M., Gulick, T., and Cooper, G.M. 1999. Identification of COUP-TF as a transcriptional repressor of the c-mos proto-oncogene. J. Biol. Chem. 274:36796-36800. *Erhardt, P., Schremser, E.J., and Cooper, G.M. 1999. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway. Mol. Cell. Biol. 19:5308-5315. *Pap, M., and Cooper, G.M. 1998. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. 273:19929-19932. *Dudek, H., Datta, S.R., Franke, T.F., Birnbaum, M.J., Yao, R., Cooper, G.M., Segal, R.A., Kaplan, D.R., and Greenberg, M.E. 1997. Regulation of neuronal survival by the Ser/Thr protein kinase Akt. Science 275:661-665. *Erhardt, P., Tomaselli, K.J., and Cooper, G.M. 1997. Identification of the MDM2 oncoproteinas a substrate for CPP32-like apoptotic proteases. J. Biol. Chem. 272:15049-15052. *Lopes, U.G., Yao, R., and Cooper, G.M. 1997. p53-dependent induction of apoptosis by proteasome inhibitors. J. Biol. Chem. 272:12893-12896. *Xu, W., and Cooper, G.M. 1995. Identification of a candidate c-mos repressor that restricts transcription of germ cell-specific genes. Mol. Cell. Biol. 15:5369-5375. *Yao, R., and Cooper, G.M. 1995. Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267:2003-2006.

References

{{DEFAULTSORT:Cooper, Geoffrey M. Boston University faculty University of Miami alumni Living people 21st-century American biologists Year of birth missing (living people) Place of birth missing (living people)