Genetic predisposition
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A genetic predisposition is a genetic characteristic which influences the possible
phenotypic In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological pr ...
development of an individual organism within a species or population under the influence of
environmental A biophysical environment is a biotic and abiotic surrounding of an organism or population, and consequently includes the factors that have an influence in their survival, development, and evolution. A biophysical environment can vary in scal ...
conditions. In medicine, genetic susceptibility to a
disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
refers to a genetic predisposition to a health problem, which may eventually be triggered by particular environmental or lifestyle factors, such as
tobacco smoking Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or simply released from the mouth, as is generally done with pipes and cigars. The practice is beli ...
or diet.
Genetic test Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, ...
ing is able to identify individuals who are genetically predisposed to certain diseases.


Behavior

Predisposition is the capacity humans are born with to learn things such as language and concept of self. Negative
environmental influences A biophysical environment is a biotic and abiotic surrounding of an organism or population, and consequently includes the factors that have an influence in their survival, development, and evolution. A biophysical environment can vary in scale f ...
may block the predisposition (ability) one has to do some things. Behaviors displayed by animals can be influenced by genetic predispositions. Genetic predisposition towards certain human behaviors is scientifically investigated by attempts to identify patterns of human behavior that seem to be invariant over long periods of time and in very different cultures. For example, philosopher Daniel Dennett has proposed that humans are genetically predisposed to have a
theory of mind In psychology, theory of mind refers to the capacity to understand other people by ascribing mental states to them (that is, surmising what is happening in their mind). This includes the knowledge that others' mental states may be different fro ...
because there has been
evolution Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
ary selection for the human ability to adopt the intentional stance. The ''intentional stance'' is a useful behavioral strategy by which humans assume that others have minds like their own. This assumption allows one to predict the behavior of others based on personal knowledge. In 1951, Hans Eysenck and Donald Prell published an experiment in which identical (monozygotic) and fraternal (dizygotic) twins, ages 11 and 12, were tested for neuroticism. It is described in detail in an article published in the ''
Journal of Mental Science A journal, from the Old French ''journal'' (meaning "daily"), may refer to: *Bullet journal, a method of personal organization *Diary, a record of what happened over the course of a day or other period *Daybook, also known as a general journal, a ...
''. in which Eysenck and Prell concluded that, "The factor of neuroticism is not a statistical artifact, but constitutes a biological unit which is inherited as a whole....neurotic Genetic predisposition is to a large extent hereditarily determined." E. O. Wilson's book on sociobiology and his book Consilience discuss the idea of genetic predisposition of behaviors. The field of
evolutionary psychology Evolutionary psychology is a theoretical approach in psychology that examines cognition and behavior from a modern evolutionary perspective. It seeks to identify human psychological adaptations with regards to the ancestral problems they evo ...
explores the idea that certain behaviors have been selected for during the course of evolution.


Genetic discrimination in health insurance in US

In US, the Genetic Information Nondiscrimination Act, which was signed into law by President Bush on May 21, 2008, prohibits discrimination in employment and health insurance based on genetic information.


See also

*
Human nature Human nature is a concept that denotes the fundamental dispositions and characteristics—including ways of thinking, feeling, and acting—that humans are said to have naturally. The term is often used to denote the essence of humankind, or ...
* Nature versus nurture * Behavioral genetics * Predispositioning Theory * Psychiatric genetics * Gene-environment correlation *
Eugenics Eugenics ( ; ) is a fringe set of beliefs and practices that aim to improve the genetic quality of a human population. Historically, eugenicists have attempted to alter human gene pools by excluding people and groups judged to be inferior o ...
* Eggshell skull * MODY *
Allergy Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derm ...
* Oncogene *
Quantitative trait locus A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs ...
* Genetic privacy


References

# The results of this survey ar
discussed here
(January 20, 1998). #
summary
of U.S.A. executive orders and proposed legislation is compiled by the National Center for Genome Resources. # ''The Intentional Stance'' (MIT Press; Reprint edition 1989) ()


External links


Genetic discrimination fact sheet from the National Human Genome Research Institute
{{DEFAULTSORT:Genetic Predisposition Genetics Behavioural sciences