GPR182 (or G protein-coupled receptor 182) is a human gene (and associated protein) which is an
orphan G-protein coupled receptor.
When this gene was first cloned, it was proposed to encode an adrenomedullin receptor.
However, when the corresponding protein was expressed, it was found not to respond to
adrenomedullin (ADM).
It was subsequently shown that a different GPCR,
CALCRL
Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein; it is a receptor for calcitonin gene-related peptide.
Function
The protein encoded by the CALCRL gene is a G protein-coupled rece ...
when complexed with
RAMP2
Receptor activity modifying protein 2, also known as RAMP2, is a protein which in humans is encoded by the ''RAMP2'' gene.
Function
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, calle ...
can function as an ADM receptor.
References
Further reading
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External links
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G protein-coupled receptors
{{transmembranereceptor-stub