Guanine nucleotide-binding protein G(k) subunit alpha is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''GNAI3''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
GNAI3 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
RGS10
Regulator of G-protein signaling 10 is a protein that in humans is encoded by the ''RGS10'' gene.
Function
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha ...
*
RGS12
Regulator of G-protein signaling 12 is a protein that in humans is encoded by the ''RGS12'' gene.
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatas ...
,
[
* ]RGS14
Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the ''RGS14'' gene.
Function
RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-bind ...
,RGS16
Regulator of G-protein signaling 16 is a protein that in humans is encoded by the ''RGS16'' gene.
Function
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing ...
,RGS18
Regulator of G-protein signaling 18 is a protein that in humans is encoded by the ''RGS18'' gene.
Function
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved 120 amino acid motif called ...
,RGS19
Regulator of G-protein signaling 19 is a protein that in humans is encoded by the ''RGS19'' gene.
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and ...
,RGS5
Regulator of G-protein signaling 5 is a protein that in humans is encoded by the ''RGS5'' gene.
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisia ...
,RIC8A
Resistance to inhibitors of cholinesterase-8A (Ric-8A), also known as Synembryn-A, is a protein that in humans is encoded by the ''RIC8A'' gene.
Interactions
RIC8A has been shown to interact with GNAO1, GNA13, GNAQ, GNAS complex locus, GNAI2, ...
,S1PR1
Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1PR1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signa ...
.
See also
* Gi alpha subunit
Gi protein alpha subunit is a family of heterotrimeric G protein alpha subunits. This family is also commonly called the Gi/o (Gi /Go ) family or Gi/o/z/t family to include closely related family members. G alpha subunits may be referred ...
References
Further reading
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{{GTPases