GALR1

Galanin receptor 1 (GAL₁) is a G-protein coupled receptor encoded by the GALR1 gene.

Function

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-trans membrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the GI/GO family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

See also

* Galanin receptor

References

Further reading

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External links

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G protein-coupled receptors

{{transmembranereceptor-stub

sr:Galaninski receptor 3