Fritz Pregl
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Fritz Pregl ( sl, Friderik Pregl; 3 September 1869 – 13 December 1930), was a Slovenian-Austrian
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe th ...
and
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
from a mixed Slovene-
German German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Ge ...
-speaking background. He won the
Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...
in 1923 for making important contributions to
quantitative Quantitative may refer to: * Quantitative research, scientific investigation of quantitative properties * Quantitative analysis (disambiguation) * Quantitative verse, a metrical system in poetry * Statistics, also known as quantitative analysis ...
organic Organic may refer to: * Organic, of or relating to an organism, a living entity * Organic, of or relating to an anatomical organ Chemistry * Organic matter, matter that has come from a once-living organism, is capable of decay or is the product ...
microanalysis Microanalysis is the chemical identification and quantitative analysis of very small amounts of chemical substances (generally less than 10 mg or 1 ml) or very small surfaces of material (generally less than 1 cm2). One of the pionee ...
, one of which was the improvement of the
combustion train Combustion analysis is a method used in both organic chemistry and analytical chemistry to determine the elemental composition (more precisely empirical formula) of a pure organic compound by combusting the sample under conditions where the resu ...
technique for
elemental analysis Elemental analysis is a process where a sample of some material (e.g., soil, waste or drinking water, bodily fluids, minerals, chemical compounds) is analyzed for its elemental and sometimes isotopic composition. Elemental analysis can be qualit ...
.


Biography

Pregl was born in
Ljubljana Ljubljana (also known by other historical names) is the capital and largest city of Slovenia. It is the country's cultural, educational, economic, political and administrative center. During antiquity, a Roman city called Emona stood in the ar ...
within
Austria-Hungary Austria-Hungary, often referred to as the Austro-Hungarian Empire,, the Dual Monarchy, or Austria, was a constitutional monarchy and great power in Central Europe between 1867 and 1918. It was formed with the Austro-Hungarian Compromise of ...
to a Slovene-speaking father and German-speaking mother. He was baptized ''Friedrich Michael Raimund Pregl''. He died in
Graz Graz (; sl, Gradec) is the capital city of the Austrian state of Styria and second-largest city in Austria after Vienna. As of 1 January 2021, it had a population of 331,562 (294,236 of whom had principal-residence status). In 2018, the popula ...
, Austria in 1930. Pregl started his career as
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe th ...
after he studied medicine at the
University of Graz The University of Graz (german: link=no, Karl-Franzens-Universität Graz, ), located in Graz, Austria, is the largest and oldest university in Styria, as well as the second-largest and second-oldest university in Austria. History The univers ...
. With his focus on
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...
and especially chemical physiology, he suffered from the limitations of
quantitative Quantitative may refer to: * Quantitative research, scientific investigation of quantitative properties * Quantitative analysis (disambiguation) * Quantitative verse, a metrical system in poetry * Statistics, also known as quantitative analysis ...
organic Organic may refer to: * Organic, of or relating to an organism, a living entity * Organic, of or relating to an anatomical organ Chemistry * Organic matter, matter that has come from a once-living organism, is capable of decay or is the product ...
microanalysis Microanalysis is the chemical identification and quantitative analysis of very small amounts of chemical substances (generally less than 10 mg or 1 ml) or very small surfaces of material (generally less than 1 cm2). One of the pionee ...
. The small quantities of substances he obtained during the research of
bile acid Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. Diverse bile acids are synthesized in the liver. Bile acids are conjugated with taurine or glycine residues to give anions called bile salts. Primar ...
made it necessary to improve the process of
elemental analysis Elemental analysis is a process where a sample of some material (e.g., soil, waste or drinking water, bodily fluids, minerals, chemical compounds) is analyzed for its elemental and sometimes isotopic composition. Elemental analysis can be qualit ...
by reducing the necessary components. At the end of his research, he had lowered the minimal amount of substance necessary for the analysis process by a factor of 50. He invited chemists to learn his method of elemental analysis, so that the method was soon widely accepted.


Commemoration

In 1950, the department of the
University of Graz The University of Graz (german: link=no, Karl-Franzens-Universität Graz, ), located in Graz, Austria, is the largest and oldest university in Styria, as well as the second-largest and second-oldest university in Austria. History The univers ...
where Fritz Pregl had worked was named the
Institute of Medical Chemistry and Pregl Laboratory An institute is an organisational body created for a certain purpose. They are often research organisations (research institutes) created to do research on specific topics, or can also be a professional body. In some countries, institutes can ...
. Streets in Graz, Innsbruck, Vienna and Klagenfurt were named after him. In Slovenia,
Pregl Award Pregl is a surname. Notable people with the name include: * Fritz Pregl (1869–1930), Slovenian and Austrian chemist and physician * Marko Pregl, 16th-century politician in Slovenia * Slavko Pregl Slavko Pregl, full name Vekoslav Pregl, (born ...
s have been bestowed annually since 2007 by the National Institute of Chemistry for the research work and for outstanding
doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ...
s. Slovenian pupils are conferred Pregl Recognition Awards, whereas secondary school students are conferred Pregl Citations for excellent results in national competitions in chemistry. A square in Ljubljana is named after Pregl. The Fritz Pregl Prize has been awarded annually since 1931 in chemistry by the Austrian Academy of Sciences from the funds left at its disposal by Pregl.


References


Further reading

* *


External links

* including the Nobel Lecture, December 11, 1923 ''Quantitative Micro-Analysis of Organic Substances'' {{DEFAULTSORT:Pregl, Fritz 1869 births 1930 deaths Austrian chemists Austrian Nobel laureates Austro-Hungarian Nobel laureates Nobel laureates in Chemistry Scientists from Ljubljana Slovenian chemists Slovenian Nobel laureates Slovenian physiologists Austrian people of Slovenian descent Rectors of universities in Austria People from Ljubljana in health professions