Frederick George Novy
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__NOTOC__ Frederick George Novy (December 9, 1864 – August 8, 1957) was an American bacteriologist, organic chemist, and instructor. Born in
Chicago, Illinois (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
, the third son of Joseph Novy and his wife Frances, grew up on the West Side, near the site where the
Great Chicago Fire The Great Chicago Fire was a conflagration that burned in the American city of Chicago during October 8–10, 1871. The fire killed approximately 300 people, destroyed roughly of the city including over 17,000 structures, and left more than 1 ...
started in 1871. After attending the local public schools, Novy matriculated to the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
where he studied chemistry, graduating with a B.S. in 1886. He performed his graduate studies at the same institution, receiving his master's degree in 1887 with a thesis on "
Cocaine Cocaine (from , from , ultimately from Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly used recreationally for its euphoric effects. It is primarily obtained from the leaves of two Coca species native to South Am ...
and its derivatives". At this time he became an instructor at the University, teaching a course in
bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...
, then was awarded an Sc.D. in 1890 with a thesis titled, "The Toxic Products of the
Bacillus ''Bacillus'' (Latin "stick") is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum '' Bacillota'', with 266 named species. The term is also used to describe the shape (rod) of other so-shaped bacteria; and the plural ''Bacill ...
of
Hog Cholera Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word ) is a highly contagious disease of swine (Old World and New World pigs). It has been mentioned as a potential bioweapon. Clinical signs Sw ...
". The following year, he completed the work needed to receive his M.D. He was married to Grace Garwood in 1891; the daughter of Dr. V. G. Garwood. Following his graduation, Dr. Novy was made Assistant Professor of Hygiene and Physiological Chemistry at the University of Michigan. He made visits overseas, to the University of Prague in 1894 and the
Pasteur Institute The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vacc ...
in 1897, where he became a friend of
Emile Roux Emil or Emile may refer to: Literature *''Emile, or On Education'' (1762), a treatise on education by Jean-Jacques Rousseau * ''Émile'' (novel) (1827), an autobiographical novel based on Émile de Girardin's early life *''Emil and the Detective ...
and improved his understanding of bacteriology. By 1900, he had gained a national reputation as the foremost national expert of the subject of bacteriology. The same year, he helped to found the
Society of American Bacteriologists The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It wa ...
. He was made full professor at Michigan in 1904 and became the first chairman of the University's Department of Bacteriology. It was early in the twentieth century that Dr. Novy began the study of trypanosomes and
spirochete A spirochaete () or spirochete is a member of the phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm (double-membrane) gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or s ...
s, for which work he is best known. He developed techniques for their cultivation, and is possibly the first to cultivate a pathogenic
protozoa Protozoa (singular: protozoan or protozoon; alternative plural: protozoans) are a group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic tissues and debris. Histo ...
n in a laboratory. Among his other work, he performed studies of
anaerobic bacteria An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenat ...
, investigated an outbreak of the
bubonic plague Bubonic plague is one of three types of plague caused by the plague bacterium ('' Yersinia pestis''). One to seven days after exposure to the bacteria, flu-like symptoms develop. These symptoms include fever, headaches, and vomiting, as wel ...
in
San Francisco San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17t ...
during 1900, researched
anaphylotoxin Anaphylatoxins, or complement peptides, are fragments ( C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement components C3, C4 and C5 are large glycoproteins that have important functions in the immu ...
, and studied the metabolism of microorganisms—especially the tubercle bacillus. In 1905, he was selected for membership on the Council on Pharmacy and Chemistry of the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's sta ...
, a position he would retain until 1930. He was the Henry L. Russell Lecturer at the University of Michigan in 1927, then in 1931 the George M. Kober Lecturer at
Georgetown University Georgetown University is a private research university in the Georgetown neighborhood of Washington, D.C. Founded by Bishop John Carroll in 1789 as Georgetown College, the university has grown to comprise eleven undergraduate and graduate ...
. In 1930, he was selected to be a gold medalist of the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's sta ...
. He continued to contribute to the scientific research in bacteriology for the remainder of his career, publishing his final scientific paper in 1953 at the age of ninety. Much of his later years were consumed by administrative work. He served as fourth president of the
Society of American Bacteriologists The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It wa ...
in 1904, and was elected the president of the American Society for Experimental Pathology in 1921 and president of the
American Association of Immunologists The American Association of Immunologists (AAI) is an international scientific society dedicated to furthering the study of immunology. AAI provides its members with a variety of platforms in which to exchange ideas and present the latest immunolo ...
in 1924. Dr. Novy was chairman of the Executive Committee for the University of Michigan Medical School during 1930–33, then during 1933–35 he served as Dean of the University Medical School. He retired in 1935. His wife, Grace Garwood, died in 1946; Dr. Novy died at his
Ann Arbor, Michigan Ann Arbor is a city in the U.S. state of Michigan and the county seat of Washtenaw County. The 2020 census recorded its population to be 123,851. It is the principal city of the Ann Arbor Metropolitan Statistical Area, which encompasses all ...
home in 1957. He was survived by three sons and two daughters. All of his sons were practicing physicians. In
Sinclair Lewis Harry Sinclair Lewis (February 7, 1885 – January 10, 1951) was an American writer and playwright. In 1930, he became the first writer from the United States (and the first from the Americas) to receive the Nobel Prize in Literature, which was ...
's 1925 novel Arrowsmith, Dr. Novy was the model for the character of Max Gottlieb.


Awards and honors

Dr. Novy was the recipient of numerous honors: * Member,
Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine." ...
, 1900 * Honorary L.L.D.,
University of Cincinnati The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,0 ...
, 1920 * Member,
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
, 1924 *
Chevalier of the Légion d'honneur The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon B ...
, 1924 * Gold medalist, American Medical Association, 1930 * Service citation from the Legislature of the State of Michigan, 1931 * Member, Order of the White Lion of Czecho-Slovakia, 1931 * Member,
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
, 1934 * Honorary L.L.D., University of Michigan, 1936


Bibliography

* ''Cocaine and its derivatives'' (1887) * ''Directions for laboratory work in urine analysis'' (1892) * ''Directions for laboratory work in bacteriology'' (1894) * ''Ptomaïns, leucomaïns, toxins and antitoxins: or, the chemical factors in the causation of disease'' (1896) with Victor Clarence Vaughan * ''Toxins & Antitoxins'' (1896) * ''Laboratory work in physiological chemistry'' (1898) * ''Laboratory work in bacteriology'' (1899) * ''Cellular toxins'' (1902) with Victor Clarence Vaughan * ''On the trypanosomes of birds'' (1905) with Ward J. MacNeal * ''Studies in Spirillum Obermeieri and related organisms'' (1906) * ''The trypanosomes of mosquitoes and other insects'' (1907) * ''Zina Pitcher'' (1908) * ''Anaphylatoxin and anaphylaxis'' (1917) with Paul Henry DeKruif and Robert Lev Novy * ''Microbic respiration'' (1925)


References


External links

* * {{DEFAULTSORT:Novy, Frederick George 1864 births 1957 deaths American bacteriologists Chevaliers of the Légion d'honneur People from Ann Arbor, Michigan Scientists from Chicago University of Michigan Medical School alumni University of Michigan faculty