Frances McConnell-Mills
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Frances Mary McConnell-Mills (July 9, 1900 – December 28, 1975) was an American
toxicologist Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expo ...
. She was the first woman to be appointed
Denver Denver () is a consolidated city and county, the capital, and most populous city of the U.S. state of Colorado. Its population was 715,522 at the 2020 census, a 19.22% increase since 2010. It is the 19th-most populous city in the Unit ...
's city toxicologist, the first female toxicologist in the
Rocky Mountains The Rocky Mountains, also known as the Rockies, are a major mountain range and the largest mountain system in North America. The Rocky Mountains stretch in straight-line distance from the northernmost part of western Canada, to New Mexico ...
, and probably the first female
forensic pathologist Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases ...
in the United States. McConnell was raised in Colorado and after studying chemistry she became a high school teacher. She later attended medical school at the
University of Colorado Denver The University of Colorado Denver (CU Denver) is a public research university in Denver, Colorado. It is part of the University of Colorado system. History University of Colorado System Anschutz Medical Campus The University of Colorado creat ...
, graduating in 1925. She specialized in the fields of
toxicology Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating e ...
and
forensic pathology Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases ...
, which led her to testify in many high-profile criminal cases throughout her career. In addition to working as Denver's city toxicologist, she held positions in multiple hospitals and administrative boards. After battling lifelong health problems, including
rheumatic heart disease Rheumatic fever (RF) is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a streptococcal throat infection. Signs and symptoms include fever, multiple painful jo ...
and a leg amputation, McConnell died in 1975. She was posthumously inducted into the
Colorado Women's Hall of Fame The Colorado Women's Hall of Fame is a non-profit, volunteer organization that recognizes women who have contributed to the history of the U.S. state of Colorado. As of 2020, 170 women have been inducted. History There was a short-lived recogniti ...
.


Early life

McConnell-Mills was born Frances Mary McConnell in 1900 in Monument, Colorado. Her father was a physician and a pharmacist, and often took Frances with him when he made house calls to patients. She was sent to live with her aunt and grandfather so that she could attend Colorado Springs High School; she graduated at the age of 15 and was awarded a full scholarship to the
University of Denver The University of Denver (DU) is a private research university in Denver, Colorado. Founded in 1864, it is the oldest independent private university in the Rocky Mountain Region of the United States. It is classified among "R1: Doctoral Univ ...
. She received a
bachelor's degree A bachelor's degree (from Middle Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate academic degree awarded by colleges and universities upon completion of a course of study lasting three to six ...
from the university in 1918, aged 17, and graduated again with a
master's degree A master's degree (from Latin ) is an academic degree awarded by universities or colleges upon completion of a course of study demonstrating mastery or a high-order overview of a specific field of study or area of professional practice.
in chemistry when she was 19, making her the university's youngest graduate with a master's degree at the time. In 1919, she began work as a teacher of chemistry, biology, geometry and trigonometry at Englewood High School. McConnell applied to the
University of Colorado School of Medicine The University of Colorado School of Medicine is the medical school of the University of Colorado system. It is located at the Anschutz Medical Campus in Aurora, Colorado, one of the four University of Colorado campuses, six miles east of downtow ...
in 1920 and was accepted. Although her father had previously paid for 17 men to attend medical school, he refused to pay for Frances' tuition because he deemed medicine to be "too hard a life for a woman". She therefore supported herself through medical school by working as a musician in local bars and theaters, as a tutor, and as a laboratory assistant. In November 1925, she married David L. Mills, a lawyer, and gave birth to a daughter the year after. Although McConnell hyphenated her name to McConnell-Mills, she continued to use her maiden name for her professional career to avoid drawing attention to her children.


Career

McConnell graduated from the University of Colorado as a
Doctor of Medicine Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
in 1925 and completed an internship at
Denver General Hospital Denver Health Medical Center, formerly named Denver General Hospital, is a hospital in the Lincoln Park neighborhood of Denver, founded in 1860. It is one of five Level I Trauma Centers in Colorado. Denver Health Medical Center is one of the ...
. She subsequently took on a position as a
toxicologist Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expo ...
in the coroner's offices at the same hospital, making her the first female toxicologist in the
Rocky Mountains The Rocky Mountains, also known as the Rockies, are a major mountain range and the largest mountain system in North America. The Rocky Mountains stretch in straight-line distance from the northernmost part of western Canada, to New Mexico ...
area. She was appointed Denver's city toxicologist in 1926 and became an assistant
pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
in 1927, working alongside deputy coroner George Bostwick and city pathologist W. S. Dennis. Her appointment to city toxicologist made her the first woman to hold the position. McConnell's work mainly focused on poison and blood analysis, and she testified in many criminal cases as an
expert witness An expert witness, particularly in common law countries such as the United Kingdom, Australia, and the United States, is a person whose opinion by virtue of education, training, certification, skills or experience, is accepted by the judge as ...
. Her work often involved determining the cause of death when poisoning was suspected. In 1930, she investigated the death of a ten-year-old Denver girl; the case was referred to at the time as the city's "most famous and controversial murder case". Although she initially suspected the girl had been poisoned, McConnell discovered crushed glass in the girl's stomach and blood stains in the family car; her testimony led to the sentencing of the girl's stepmother for murder. In 1936, McConnell testified against suspected rapist and murderer Joe Arridy after finding fibers from the bedspread at the murder scene under the suspect's fingernails. (Although Arridy was convicted of murder and executed in 1939, he was granted a posthumous pardon in 2011.) McConnell also discovered that murder victim Georg Obendoerfer had been killed with a lethal dose of
arsenic Arsenic is a chemical element with the symbol As and atomic number 33. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. Arsenic is a metalloid. It has various allotropes, ...
, which led to further investigations confirming that
Anna Marie Hahn Anna Marie Hahn (born Filser; July 7, 1906 – December 7, 1938) was a German-born American serial killer. Biography Early life Anna Hahn was the youngest of twelve children though five of her siblings had died by the time Anna was born. Her f ...
had killed Obendoerfer, as well as other men in the same way. McConnell testified at Hahn's trial in
Cincinnati Cincinnati ( ) is a city in the U.S. state of Ohio and the county seat of Hamilton County. Settled in 1788, the city is located at the northern side of the confluence of the Licking and Ohio rivers, the latter of which marks the state line wit ...
and Hahn was subsequently convicted and executed. After she was called to
Raton, New Mexico Raton ( ) is a city and the county seat of Colfax County in northeastern New Mexico. The city is located just south of Raton Pass. The city is also located about 6.5 miles south of the New Mexico–Colorado border and 85 miles west of Texas. His ...
as a key witness in a murder trial in 1935, a court reporter for the '' Raton Range'' wrote that McConnell "has gained a national reputation ... in her blood analysis work". Additionally, she is thought to be the United States' first female
forensic pathologist Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases ...
. Despite working on numerous high-profile, widely publicized cases, McConnell kept her life as private as possible and only ever gave one interview during her career. Outside of toxicology, McConnell did extensive laboratory work. In the 1930s and 1940s she undertook personal research into
passive immunity Passive immunity is the transfer of active humoral immunity of ready-made antibodies. Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and it can also be induced artificially, when ...
and developed serums for scarlet fever,
polio Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe s ...
, the common cold and
acne Acne, also known as ''acne vulgaris'', is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and ...
for use on family members. While working for
otolaryngologist Otorhinolaryngology ( , abbreviated ORL and also known as otolaryngology, otolaryngology–head and neck surgery (ORL–H&N or OHNS), or ear, nose, and throat (ENT)) is a surgical subspeciality within medicine that deals with the surgical a ...
Harry Baum, she invented a hair rinse which Baum called "Noreen" that was produced until the 1990s. In 1941, she was appointed director of the laboratory department of the Colorado State Board of Health, and she later founded Denver General Hospital's School for Medical Technologists in order to train new workers, especially women. She enrolled in an advanced
serology Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given mic ...
training program at the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
in 1941 and went on to study
surgical pathology Surgical pathology is the most significant and time-consuming area of practice for most anatomical pathologists. Surgical pathology involves gross and microscopic examination of surgical specimens, as well as biopsies submitted by surgeons and ...
at the
Cook County Hospital The John H. Stroger Jr. Hospital of Cook County (formerly Cook County Hospital) is a public hospital in Chicago, Illinois, United States. It is part of the Cook County Health and Hospital System, along with Provident Hospital of Cook County and ...
in
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
in 1943. Following her term at Cook County, she resigned from the Board of Health and accepted a role at St. Luke's Hospital in Denver as a laboratory director and pathologist. She was forced to leave St. Luke's in 1944 due to illness, and after recovering she returned to Denver General Hospital as its laboratory director. She continued to work on criminal cases between other jobs until 1948. In the 1950s, McConnell joined physician and
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
activist Florence R. Sabin to create an examination on behalf of the Colorado State Board of Basic Sciences for granting licenses to applicants who wished to practice health science. McConnell was appointed to the Board in 1956, making her the only female member at the time, and served until 1975.


Health problems and death

McConnell battled with health problems throughout her life, after contracting rheumatic fever at the age of 20 which subsequently progressed to
rheumatic heart disease Rheumatic fever (RF) is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a streptococcal throat infection. Signs and symptoms include fever, multiple painful jo ...
. In 1944 she contracted
appendicitis Appendicitis is inflammation of the appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, and decreased appetite. However, approximately 40% of people do not have these typical symptoms. Severe complications of a ru ...
which required an emergency appendectomy; she developed
deep vein thrombosis Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly in the legs or pelvis. A minority of DVTs occur in the arms. Symptoms can include pain, swelling, redness, and enla ...
in her right leg after the surgery and her leg was subsequently amputated above the knee. She was given a
prosthetic In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
leg which she named "Matilda" but later needed to use a wheelchair. Following the death of her husband in 1967, McConnell lived alone. She kept working until the last two weeks of her life, filling various roles on the Board of Basic Sciences, in an allergy practice, and as a consultant for the Denver Poison Center. She died in December 1975 in St. Luke's Hospital, Denver, at the age of 75.


Legacy

A year before her death, in December 1974, McConnell received an award from the University of Colorado Medical School which recognized her as a 50-year graduate of the school and as one of only two Coloradoan women at the time who had practiced medicine for 50 years. She was inducted into the
Colorado Women's Hall of Fame The Colorado Women's Hall of Fame is a non-profit, volunteer organization that recognizes women who have contributed to the history of the U.S. state of Colorado. As of 2020, 170 women have been inducted. History There was a short-lived recogniti ...
in 1996. In 1999, her daughter Jeanne Varnell published a book titled ''Women of Consequence: The Colorado Women's Hall of Fame'', which contains the biographies of McConnell and 58 other inductees of the Hall of Fame. The project began when Varnell set out to write a biography of her mother, but was urged by her editor to do the same for all 59 of the women in the Hall of Fame at the time, and compile them into a book.


References


Works cited

* {{DEFAULTSORT:McConnell-Mills, Frances 1900 births 1975 deaths American women scientists People from Denver People from Monument, Colorado Physicians from Colorado American toxicologists Women inventors University of Colorado School of Medicine alumni University of Denver alumni 20th-century American physicians 20th-century American women physicians