Fluorodeoxyglycosylamine
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Fluorodeoxyglycosylamine is a product of
fluorodeoxyglucose 18F.html" ;"title="sup>18F">sup>18Fluorodeoxyglucose ( INN), or fluorodeoxyglucose F 18 (USAN and USP), also commonly called fluorodeoxyglucose and abbreviated 18F.html" ;"title="sup>18F">sup>18FDG, 2- 18F.html" ;"title="sup>18F">sup>18FDG or ...
and biological amines. The
Maillard reaction The Maillard reaction ( ; ) is a chemical reaction between Amino acid, amino acids and Reducing sugar, reducing sugars that gives browned food its distinctive flavor. Searing, Seared steaks, fried dumplings, cookies and other kinds of biscuits, b ...
of sugars and amines results in the formation of glycosylamines and
Amadori product The Amadori rearrangement is an organic reaction describing the acid or base catalyzed isomerization or rearrangement reaction of the ''N''-glycoside of an aldose or the glycosylamine to the corresponding 1-amino-1- deoxy- ketose. The reaction i ...
s that are of biological significance, for drug delivery, role in central nervous system, and other potential applications. This approach has also been used to prepare
oximes In organic chemistry, an oxime is a organic compound belonging to the imines, with the general formula , where R is an organic side-chain and R’ may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime. O-substitute ...
of fluorodeoxyglucose using peptides, folic acid and rhodamine. Fluorodeoxyglycosylamine in the form of fluorodeoxyglycosylamines ( 18F) may be reduced to provide fluorodeoxyglucamine (18F) as a positron emission tomography (PET)
radiotracer A radioactive tracer, radiotracer, or radioactive label is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tr ...
.


References

{{pharma-stub Amino sugars Deoxy sugars Organofluorides Medicinal radiochemistry PET radiotracers