Yermo may refer to:
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Yermo, California
Yermo (Spanish for "wilderness") is an unincorporated community in the Mojave Desert in San Bernardino County, California. It is east of Barstow on Interstate 15, just south of the Calico Mountains. Its population was an estimated 1,750 in 20 ...
, a town in the United States
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''Yermo'' (plant), a genus of the tribe Senecioneae and the family Asteraceae
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José Maria Yermo, Spanish footballer
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