Thymidine monophosphate (TMP), also known as thymidylic acid (
conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (
conjugate base deoxythymidylate), is a
nucleotide that is used as a
monomer in
DNA. It is an
ester of
phosphoric acid with the
nucleoside thymidine. dTMP consists of a
phosphate group, the
pentose sugar
Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double ...
deoxyribose, and the
nucleobase thymine. Unlike the other
deoxyribonucleotide
A deoxyribonucleotide is a nucleotide that contains deoxyribose. They are the monomeric units of the informational biopolymer, deoxyribonucleic acid ( DNA). Each deoxyribonucleotide comprises three parts: a deoxyribose sugar (monosaccharide), a ni ...
s, thymidine monophosphate often does not contain the "deoxy" prefix in its name; nevertheless, its symbol often includes a "d" ("dTMP").
''Dorland’s Illustrated Medical Dictionary''
provides an explanation of the nomenclature variation at its entry for thymidine.
As a
substituent
A substituent is one or a group of atoms that replaces (one or more) atoms, thereby becoming a moiety in the resultant (new) molecule. (In organic chemistry and biochemistry, the terms ''substituent'' and ''functional group'', as well as ''side ...
, it is called by the prefix thymidylyl-.
See also
*
DNA
*
Nucleoside
*
Nucleotide
*
Oligonucleotide
*
RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...
References
Nucleotides
Phosphate esters
{{Organic-chemistry-stub
