Interstate 880 may refer to:
*Interstate 880 (California), an auxiliary Interstate Highway that travels from San Jose to Oakland, California
**Interstate 880 (California 1964–1981), a former auxiliary Interstate Highway in Sacramento, California
*Interstate 880 (Iowa), an auxiliary Interstate Highway in Pottawattamie County, Iowa
{{Road disambiguation
Interstate 80, 8
Auxiliary Interstate Highways, 80-8
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