Interstate 280 may refer to multiple highways, all of which are or were related to
Interstate 80
Interstate 80 (I-80) is an east–west transcontinental freeway that crosses the United States from downtown San Francisco, California, to Teaneck, New Jersey, in the New York metropolitan area. The highway was designated in 1956 as one o ...
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Interstate 280 (California), a north–south freeway running from San Jose to San Francisco
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Interstate 280 (Iowa–Illinois)
Interstate 280 (I-280) is an auxiliary Interstate Highway that makes up the western and southern portions of the beltway around the Quad Cities of Illinois and Iowa. The freeway starts at Interstate 80 in Iowa, I-80 near Davenport, Iowa, a ...
, part of the beltway around the Quad Cities
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Interstate 280 (New Jersey), a connector from Interstate 80 to Interstate 95 in Newark
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Interstate 280 (Ohio)
Interstate 280 (I-280) is a auxiliary Interstate Highway in Ohio that connects Interstate 75 in Ohio, I-75 in northeast Toledo, Ohio, Toledo with Interstate 80 in Ohio, I-80/Interstate 90 in Ohio, I-90 (part of the Ohio Turnpike) southeast ...
, a connector in Toledo from Interstates 80/90 to Interstate 75
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Interstate 276
The Pennsylvania Turnpike (Penna Turnpike or PA Turnpike) is a toll highway operated by the Pennsylvania Turnpike Commission (PTC) in the U.S. state of Pennsylvania. A controlled-access highway, it runs for across the state. The turnpike's we ...
, once designated as I-280 when I-76 was I-80S
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Interstate 680 (Nebraska–Iowa)
Interstate 680 (I-680) in Nebraska and Iowa is the northern bypass of the Omaha–Council Bluffs metropolitan area. I-680 spans from its southern end in western Omaha, Nebraska, to its eastern end near Crescent, Iowa. The freeway passes ...
, once designated as I-280
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