Descanso may refer to:
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Descanso (roadside memorial)
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''Descanso'' (spider), a genus of jumping spider
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Descanso, California
Descanso (Spanish for "Rest"; Kumeyaay: ''Wataay'') is a small unincorporated community in the Cuyamaca Mountains, within the Mountain Empire area of southeastern San Diego County, California. The community's name is a Spanish word meaning "rest fr ...
, an unincorporated community in the United States
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Descanso, Santa Catarina, a town and municipality in Brazil
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Descanso Gardens, a botanical garden in La Cañada Flintridge, California
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