''Colpodella'' is a genus of Alveolata, alveolates comprising 5 species, and two further possible species: They share all the synapomorphy, synapomorphies of apicomplexans, but are free-living, rather than parasitism, parasitic. Many members of this genus were previously assigned to a different genus - ''Spiromonas''. The type species is ''Colpodella pugnax'' Cienkowski 1865.

Description

These are small (< 20 micrometre, μm in diameter) flagellated protists. The biological life cycle, life cycle of consists of two main stages: flagellum, flagellated trophozoites and Microbial cyst, cysts, which are the reproductive stage in the life cycle. Morphologically the trophozoites of ''Colpodella'' are similar to ''Perkinsus'' zoospores, although the two taxa are not specifically related. The motile stages of both genera have a pair of anterior orthogonal flagella, vesicular mitochondrial cristae, inner alveolar membranes and micropores. Both ''Colpodella'' and ''Perkinsus'' species have open sided truncated conoids (sometimes called pseudoconoids), rhoptry, rhoptries that occupy the length of the cell and smaller micronemes. Both the rhoptries and micronemes arise at the anterior portion of the cell. A three-layered pellicle lies beneath the plasma membrane and is otherwise composed of the alveolar membranes and widely separated microtubules that arise subapically. Some species have extrusive organelles (trichocysts). Unlike ''Perkinsus'', ''Colpodella'' are free-living and are voracious predators of other free-living protists. Most species apparently penetrate through the cell membrane and consume the prey's cytoplasm - this mode of feeding is known as myzocytosis. While feeding the predator attaches its anterior portion - the rostrum - to the prey. The rostrum contains the pseudoconoid, which transforms into a ring of microtubules encircling the attachment zone. The cytoplasm of the prey is then drawn into a large posterior food vacuole. Following feeding cells lose their flagella, become spherical, encyst and divide (i.e. reproduce). The microbial cyst, cysts are simple spheres. The food vacuole appears as a large central vacuole in the cyst; as division progresses the remnant vacuole material is reduced to a residual body. Typically Colpodella divides into four daughter cells (sometimes just two). This is in contrast to true Apicomplexa and ''Perkinsus'', which typically produce many more daughter cells during reproduction - ''Perkinsus'' species can produce up to 32 cells, for example, while ''Toxoplasma'' produces 128. The daughter cells grow flagella, the cyst wall ruptures, and the cells swim away, leaving the residual body behind. A possible sexual process has been observed in at least two species.

Taxonomy

This family appears to be a sister clade to the Apicomplexa. Their life style may be representative of the free living ancestors of the Apicomplexa. One significant difference is that this genus, like the Perkinsea, have an open sided conoid (pseudoconoid) while the Apicomplexa which possess a conoid (the Conoidasida) have a closed conoid. Another genus in this family is ''Acrocoelus''. Species currently within genus: * ''Colpodella edax'' (Klebs 1892) Simpson & Patterson 1996 * ''Colpodella pseudoedax'' Mylnikov & Mylnikov 2007 * ''Colpodella pugnax'' Cienkowsky 1865 non Simpson & Patterson 1996 * ''Colpodella angusta'' (Dujardin 1841) Simpson & Patterson 1996 [''Dingensia angusta'' (Dujardin 1841) Patterson & Zoelffel 1991] Species transferred to other genera: * ''Colpodella gonderi'' (Foissner & Foissner 1984) Simpson & Patterson 1996 as ''Microvorax gonderi'' (Foissner & Foissner 1984) Cavalier-Smith 2017 * ''Colpodella perforans'' (Hollande 1938) Patterson & Zölffel 1991 as ''Chilovora perforans'' (Hollande 1938) Cavalier-Smith & Chao 2004 * ''Colpodella pontica'' Mylnikov 2000 as ''Voromonas pontica'' (Mylnikov 2000) Cavalier-Smith & Chao 2004 * ''Colpodella pugnax'' Simpson & Patterson 1996 non Cienkowsky 1865 as ''Algovora pugnax'' (Simpson & Patterson 1996) Cavalier-Smith & Chao 2004 * ''Colpodella tetrahymenae'' Cavalier-Smith 2004 as ''Microvorax tetrahymenae'' (Cavalier-Smith & Chao 2004) Cavalier-Smith 2017 * ''Colpodella turpis'' Simpson & Patterson 1996 as ''Algovora turpis'' (Simpson & Patterson 1996) Cavalier-Smith & Chao 2004 * ''Colpodella unguis'' Patterson & Simpson 1996 as ''Colpovora unguis'' (Patterson & Simpson 1996) Cavalier-Smith 2017 * ''Colpodella vorax'' (Kent, 1880) Simpson & Patterson, 1996 as ''Dinomonas vorax'' Kent 1880

Clinical

These organisms are not normally considered to be human pathogens. However, a report of an infection of the erythrocytes in a Chinese woman with a deficiency of natural killer cells has been reported.Yuan CL, Keeling PJ, Krause PJ, Horak A, Bent S, Rollend L, Hua XG (2012) ''Colpodella'' spp.-like parasite infection in woman, China. Emerg Infect Dis 18(1):125-127 doi: 10.3201/eid1801.110716

References

External links

* {{Taxonbar, from=Q5149298 Apicomplexa genera