Cholula may refer to:

Places

* Cholula (Mesoamerican site), a pre-Columbian archaeological site in central Mexico, significant political center in the Classic and Postclassic eras of Mesoamerican chronology ** Great Pyramid of Cholula, the pyramid-temple complex situated at the pre-Columbian site * Cholula, Puebla, the modern-day city in Puebla state, Mexico, formal name ''Cholula de Rivadavia'' * San Andrés Cholula (municipality), San Andrés Cholula, modern-day Mexican ''municipio'' (municipality), part of the conurbation of the city of Puebla * San Pedro Cholula, modern-day Mexican ''municipio'' (municipality), part of the conurbation of the city of Puebla * Santa Isabel Cholula, modern-day Mexican ''municipio'' (municipality), largely rural adjoining the conurbation of the city of Puebla

Products

* Cholula Hot Sauce, commercial brand of chili-based sauce manufactured in Jalisco, Mexico {{disambiguation, geo