Cancell, also called Protocel, Sheridan's Formula, Jim's Juice, Crocinic Acid, JS–114, JS–101, 126–F, and Entelev, is a formula that has been promoted as a treatment for a wide range of diseases, including cancer. Cancell is available in tablet and liquid form. Originally called Entelev, the formula was developed by

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

James V. Sheridan. Sheridan sought to target the primarily anaerobic cell metabolism of cancer cells (following the theories of

Otto Warburg Otto Warburg may refer to: *Otto Warburg (botanist) (1859–1938), German botanist *Otto Heinrich Warburg Otto Heinrich Warburg (, ; 8 October 1883 – 1 August 1970), son of physicist Emil Warburg, was a German physiologist, medical doctor, and ...

), claiming to lower cell potential leading to the destruction of cancer cells. The Cancell formula was tested by the National Cancer Institute and found to be ineffective against cancer, though Cancell continues to be marketed as a

dietary supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order ...

in the US.

Formulation and efficacy

The U.S. Food and Drug Administration (FDA) has listed the components as

inositol Inositol, or more precisely ''myo''-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and ...

, nitric acid, sodium sulfite, potassium hydroxide,

sulfuric acid Sulfuric acid (American spelling and the preferred IUPAC name) or sulphuric acid ( Commonwealth spelling), known in antiquity as oil of vitriol, is a mineral acid composed of the elements sulfur, oxygen and hydrogen, with the molecular formu ...

, and catechol. Precise formulation varies by manufacturer, and may include

crocinic acid Cancell, also called Protocel, Sheridan's Formula, Jim's Juice, Crocinic Acid, JS–114, JS–101, 126–F, and Entelev, is a formula that has been promoted as a treatment for a wide range of diseases, including cancer. Cancell is available in tabl ...

and various minerals and vitamins. Researchers at the National Cancer Institute (NCI) tested the constituents of Cancell in animal experiments in 1978 and 1980 and ''in vitro'' on human tumors in 1990 and 1991. They concluded that the compounds comprising Cancell could not be taken in doses high enough to kill cancer cells in the body, and that further study was not warranted. No peer-reviewed clinical or animal trials of Cancell have demonstrated any positive effect; claims for Cancell's efficacy are limited to anecdotal reports and

testimonial In promotion and advertising, a testimonial or show consists of a person's written or spoken statement extolling the virtue of a product. The term "testimonial" most commonly applies to the sales-pitches attributed to ordinary citizens, where ...

s. The

American Cancer Society The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than ...

and Memorial Sloan-Kettering Cancer Center recommend against the use of CanCell, as there is no evidence that it is effective in treating any disease, and its proposed method of action is not consistent with modern science.

Legal status

Injunction proceedings were instigated by the FDA in June 1987 for manufacturing compliance violations and failure to maintain complaints files. A complaint for permanent injunction was filed February 21, 1989 in the U.S. District Court for the Eastern District of Michigan to enjoin Sheridan and Edward J. Sopcak from distributing CanCell. At a hearing in November 1992, the Court found Sopcak to be in civil contempt and ordered him to comply with the injunction immediately. Cancell is currently distributed as a dietary supplement under the names ''Protocel'' and ''Entelev'', and is not approved by the FDA for use as a cancer treatment or for any other purpose. Since it is marketed as a dietary supplement with no health claims attached, its regulation falls under the

Dietary Supplement Health and Education Act of 1994 The Dietary Supplement Health and Education Act of 1994 ("DSHEA"), is a 1994 statute of United States Federal legislation which defines and regulates dietary supplements. Under the act, supplements are regulated by the FDA for Good Manufacturing P ...

(DSHEA).

References

External links

Cancell
entry in the public domain NCI Dictionary of Cancer Terms *
Questionable methods of cancer management: Cancell/Entelev
from the

{{NCI-cancer-dict Patent medicines Alternative cancer treatments Health fraud

Formulation and efficacy

Legal status

See also

References

External links