CGN may refer to:
* CGN, a gene that encodes for the protein cingulin
* Ceredigion, formerly ''Cardiganshire'', historic county in Wales, Chapman code
* China General Nuclear Power Group, a Chinese energy company
* ''Compagnie Générale de Navigation sur le lac Léman'', a Swiss company operating boats on Lake Léman
* Childhood gender nonconformity, a childhood behavioral pattern
* CGN, IATA code for Cologne Bonn Airport, Germany
* CGN, National Rail station code for Cogan railway station, Wales
* CGN, U.S. Navy designation for a nuclear-powered guided missile cruiser
* Carrier-grade NAT, an approach to IPv4 network design where end sites are configured with private network addresses
* CGN, cis Golgi network, compartment of the Golgi apparatus
*Crescentic glomerulonephritis, a syndrome of the kidney that is characterized by a rapid loss of kidney function
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* CGN, Computer Glitch Ninjas, A computer hardware and software hacker collective.
