CFB may refer to:
*College football
*Canadian Forces base, military installation of the Canadian forces
*Caminho de Ferro de Benguela, railway in Angola
*Carrollton-Farmers Branch Independent School District
*Block_cipher_modes_of_operation#Cipher_feedback_(CFB), Cipher feedback, a block cipher mode in data encryption
*Clube de Futebol «Os Belenenses», a football club in Portugal
*Continental flood basalt, large volumes of dominantly tholeiitic basalt on continents
*Complement factor B, a protein
*Compact fluorescent lamp, Compact fluorescent bulb
*Current-feedback operational amplifier, Current feedback, a type of electronic feedback used in some operational amplifiers
*Circulating fluidized bed, a type of fluidized bed used in power plants
*Commission fédérale des banques (Swiss Federal Banking Commission)
*CFB, the IATA code for Cabo Frio International Airport
*CFB, the National Rail station code for Catford Bridge railway station
*CFB is acronym for Call Forwarding when Busy telecom service
*Circulating fluidized bed combustion
*Cfb, one of four symbols for the Oceanic climate under the Köppen climate classification system
*Cytophaga-Flavobacteria-Bacteroides group, a previous name for the current Bacteroidota phylum
*Change From Baseline, a tool used in Clinical trial, clinical trials to measure the safety and efficacy of therapeutic interventions
*Swedish Central Federation for Voluntary Military Training
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