Escherichia
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''Escherichia'' () is a
genus Genus ( plural genera ) is a taxonomic rank used in the biological classification of living and fossil organisms as well as viruses. In the hierarchy of biological classification, genus comes above species and below family. In binomial nom ...
of
Gram-negative Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wa ...
, non- spore-forming, facultatively anaerobic, rod-shaped
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...
from the family Enterobacteriaceae. In those species which are inhabitants of the gastrointestinal tracts of
warm-blooded Warm-blooded is an informal term referring to animal species which can maintain a body temperature higher than their environment. In particular, homeothermic species maintain a stable body temperature by regulating metabolic processes. The on ...
animals, ''Escherichia'' species provide a portion of the microbially derived vitamin K for their host. A number of the species of ''Escherichia'' are
pathogen In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a g ...
ic. The genus is named after
Theodor Escherich Theodor Escherich (; 29 November 1857 – 15 February 1911) was a German- Austrian pediatrician and a professor at universities in Graz and Vienna. He discovered and described the bacterium ''Escherichia coli''. Life and achievements Fam ...
, the discoverer of ''
Escherichia coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus '' Esc ...
''. ''Escherichia'' are facultative aerobes, with both aerobic and anaerobic growth, and an optimum temperature of 37 °C. ''Escherichia'' are usually motile by flagella, produce gas from fermentable carbohydrates, and do not decarboxylate lysine or hydrolyze arginine. Species include '' E. albertii'', '' E. fergusonii'', '' E. hermannii'', '' E. marmotae'' and most notably, the model organism and clinically relevant '' E. coli''. ''
Shimwellia blattae ''Shimwellia blattae'' (formerly ''Escherichia blattae'') is a species of bacterium, one of two in the genus '' Shimwellia''. It is an aerobic enteric bacterium first isolated from the hindgut of cockroaches. Although it is related to human path ...
'' was formerly classified in this genus.


Pathogenesis

While many ''Escherichia'' are commensal members of the gut microbiota, certain strains of some species, most notably the pathogenic serotypes of '' E. coli'', are human pathogens, and are the most common cause of urinary tract infections, significant sources of gastrointestinal disease, ranging from simple
diarrhea Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin w ...
to
dysentery Dysentery (UK pronunciation: , US: ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications ...
-like conditions, as well as a wide range of other pathogenic states classifiable in general as colonic escherichiosis. While ''E. coli'' is responsible for the vast majority of ''Escherichia''-related pathogenesis, other members of the genus have also been implicated in human disease. ''Escherichia'' are associated with the imbalance of microbiota of the lower reproductive tract of women. These species are associated with inflammation.


See also

* ''E. coli'' O157:H7 * List of bacterial genera named after personal names


References


External links


Escherichia
genomes and related information a
PATRIC
a Bioinformatics Resource Center funded b
NIAID
{{Taxonbar, from=Q311055 Gut flora bacteria Gram-negative bacteria Pathogenic bacteria Bacteria genera