Epiphysiodesis
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Epiphysiodesis is a
pediatric Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
orthopedic surgery procedure that aims at altering or stopping the bone growth naturally occurring through the growth plate also known as the physeal plate. There are two types of epiphysiodesis: temporary hemiepiphysiodesis and permanent epiphysiodesis. Temporary hemiepiphysiodesis is also known as guided growth surgery or growth modulation surgery. Temporary hemiepiphysiodesis is reversible i.e. the metal implants used to achieve epiphysiodesis can be removed after the desired correction is achieved and the growth plate can thus resume its normal growth and function. In contrast, permanent epiphysiodesis is irreversible and the growth plate function cannot be restored after surgery. Both temporary hemiepiphysiodesis and permanent epiphysiodesis are used to treat a diverse array of pediatric orthopedic disorders but the exact indications for each procedure are different.


Guided growth temporary hemiepiphysiodesis

Temporary hemiepiphysiodesis is widely used to treat angular or coronal plane deformities around the knee in children i.e. deformities occurring in the medial/lateral plane as
genu varum Genu varum (also called bow-leggedness, bandiness, bandy-leg, and tibia vara) is a varus deformity marked by (outward) bowing at the knee, which means that the lower leg is angled inward ( medially) in relation to the thigh's axis, giving th ...
/ genu valgum. Additionally, it has been used to treat sagittal plane deformities i.e. deformities arising the anterior/posterior plane. Temporary hemiepiphysiodesis has also been used to treat deformities around the hips and ankles and in the upper extremity growth plates such as the distal radius growth plate. Temporary hemiepiphysiodesis works through arresting or inhibiting the physeal growth at one hemi-side of the growth plate. In consequence the other hemi-side is allowed to grow normally and unhindered. This process occurs gradually and steadily and eventually leads to correction of the angular deformity in most cases. Temporary hemiepiphysiodesis or guided growth surgery has been used to treat angular deformities in children with diverse bone and joint disorders such as
rickets Rickets is a condition that results in weak or soft bones in children, and is caused by either dietary deficiency or genetic causes. Symptoms include bowed legs, stunted growth, bone pain, large forehead, and trouble sleeping. Complications ma ...
,
Blount's disease Blount's disease (or Blount disease) is a growth disorder of the tibia (shin bone) which causes the lower leg to angle inward, resembling a bowleg. It is also known as "tibia vara". Description and risk factors Blount disease is a growth disorder ...
,
osteochondrodysplasias Osteochondrodysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro"). Osteochondrodysplasias are rare diseases. About 1 in 5,000 babies are born with some type of skeletal dysplasia. Non ...
,
arthrogryposis Arthrogryposis (AMC) describes congenital joint contracture in two or more areas of the body. It derives its name from Greek, literally meaning "curving of joints" (', "joint"; ', late Latin form of late Greek ', "hooking"). Children born with one ...
multiplex congenita,
idiopathic An idiopathic disease is any disease with an unknown cause or mechanism of apparent spontaneous origin. From Greek ἴδιος ''idios'' "one's own" and πάθος ''pathos'' "suffering", ''idiopathy'' means approximately "a disease of its own kin ...
, trauma, and renal osteodystrophy among others. Temporary hemiepiphysiodesis is increasingly been viewed as more simple and efficient alternative to the classic time-honored osteotomy or bone cutting practice. Bone osteotomy achieve deformity correction immediately while temporary hemiepiphysiodesis does so gradually. A variety of metal implants have been used to perform temporary hemiepiphysiodesis or guided growth surgery as a two-hole plate and screws and staples. Figure 1 Any metal implant originally used to achieve temporary hemiepiphysiodesis should be removed once the intended deformity correction is reached. Otherwise the child will go into the reverse deformity, a phenomenon known as overcorrection. For example, failure to remove the metal implant in due time for a child that was being treated for a
genu varum Genu varum (also called bow-leggedness, bandiness, bandy-leg, and tibia vara) is a varus deformity marked by (outward) bowing at the knee, which means that the lower leg is angled inward ( medially) in relation to the thigh's axis, giving th ...
can result in overcorrection to a genu valgum deformity and vice versa.


Outcome and complications

Generally, the results of temporary hemiepiphysiodesis or guided growth surgery are satisfactory. In contrast to osteotomy or external fixation correction, it is considered as a less traumatic and safe surgical method. The complications are of low profile in terms of severity and frequency generally. Yet, there are concerns about the use of temporary hemiepiphysiodesis in certain diseases as
Blount's disease Blount's disease (or Blount disease) is a growth disorder of the tibia (shin bone) which causes the lower leg to angle inward, resembling a bowleg. It is also known as "tibia vara". Description and risk factors Blount disease is a growth disorder ...
and
osteochondrodysplasias Osteochondrodysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro"). Osteochondrodysplasias are rare diseases. About 1 in 5,000 babies are born with some type of skeletal dysplasia. Non ...
. Mechanical failure of the metal implant as plate and screws and failure to achieve full correction of the deformity has been closely associated with the
Blount's disease Blount's disease (or Blount disease) is a growth disorder of the tibia (shin bone) which causes the lower leg to angle inward, resembling a bowleg. It is also known as "tibia vara". Description and risk factors Blount disease is a growth disorder ...
. Additionally, recurrence of bone deformity or rebound phenomenon and subsequent repeated surgeries has been closely linked to bone deformities arising from
osteochondrodysplasias Osteochondrodysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro"). Osteochondrodysplasias are rare diseases. About 1 in 5,000 babies are born with some type of skeletal dysplasia. Non ...
. Generally, children should be followed up for deformity recurrence or rebound after removal of the metal implant used to achieve deformity correction.


Permanent epiphysiodesis


Outcome and complications

The procedure must be performed for an appropriate duration during the patient's adolescent growth phase so that the limbs are near-equal in length by the end of skeletal growth. Poor timing can lead to a length mismatch, resulting in poor outcomes and significant patient morbidity.


References


Leg lengthening/shortening
{{Operations and other procedures on the musculoskeletal system Orthopedic surgical procedures