Edith E. Sproul
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Edith E. Sproul, M.D. (October 17, 1907 – January 19, 1999) was an American pathologist whose work with Georgios Papanikolaou of the
Cornell University Medical School The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with NewY ...
in New York led to the development of the
pap smear The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), cervical smear (BE), cervical screening (BE), or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in t ...
. Sproul described the relationship between
thrombophlebitis Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). When it occurs repeatedly in different locations, it is known as thrombophlebitis migrans ( migratory thrombophlebitis). Signs and symptoms The following ...
and pancreatic cancer and characteristics of early prostatic cancer.


Life and career

Edith E. Sproul was born in 1907 in Passaic, New Jersey. She graduated from
Barnard College Barnard College of Columbia University is a private women's liberal arts college in the borough of Manhattan in New York City. It was founded in 1889 by a group of women led by young student activist Annie Nathan Meyer, who petitioned Columbia ...
of Columbia University in 1927, followed by Columbia's College of Physicians and Surgeons in 1931. After a two-year internship at Strong Memorial Hospital in Rochester, New York and a residency in pathology at Presbyterian Hospital, Sproul returned to Columbia as instructor in pathology at the College of Physicians and Surgeons. She remained at Columbia for twelve years and was promoted to the position of associate professor before her departure in 1946. She then moved to the American University of Beirut in
Lebanon Lebanon ( , ar, لُبْنَان, translit=lubnān, ), officially the Republic of Lebanon () or the Lebanese Republic, is a country in Western Asia. It is located between Syria to Lebanon–Syria border, the north and east and Israel to Blue ...
, where she was appointed full professor and served as acting chair of the department of pathology. Sproul returned to Columbia in 1950 and was offered a full professorship in 1961. However, she left the University to join her husband, Arnold Mittelman, M.D. at
Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The ...
in Buffalo, New York. Here, she served as Associate Chief of Cancer Research and, in 1969, was appointed chair of the department of experimental pathology and Clinical Professor of Pathology. After her death in 1999, her former student from the American University of Beirut, Dr. Henry A. Azar, wrote, "She was for most of us the first and only woman-teacher or woman-in-authority we knew until then, and she was dazzlingly brilliant. Ours seemed, on the surface, a male-dominated world. . . she undoubtedly was a pioneer in a daring and noble form of feminism."


Publications

The following is a partial list of publications by Sproul: * Sproul, E.E. (1980) Acid phosphatase and prostate cancer: historical overview. ''The Prostate'', 1(4), 411-413. * Sproul, E.E. (1973) Projected multidisciplinary lymphoma study group. ''Journal of Surgical Oncology'', 5(6), 581-582. * Sproul, E.E. (1963) Wegener's and Lethal Midline Granulomatosis. ''JAMA: The Journal of the American Medical Association'', 177(13), 921-922. * Hudson, P.B., Sanger, G., Sproul E.E. (1959) Effective system of bactericidal conditioning for hospitals. ''Journal of the American Medical Association'', 169(14), 1549-1556. * Bickerman, H.A., Sproul, E.E., Barach, A.L. (1959) Effective system of bactericidal conditioning for hospitals. ''Diseases of the Chest'', 33(4), 347. * Fiala, A., Fiala, S., Sproul, E.E. (1956) The Action of Corticotropin (ACTH) on Nucleic Acids and Subcellular Elements of the Adrenal Cortex. ''The Journal of Biophysical and Biochemical Cytology'', 2(2), 115-126. * Fiala, S., Sproul, E.E., Blutinger, M.E., Fiala, A.E. (1955) Basophilic chromidia and mitochondria in normal and in tumor tissue. ''The Journal of Histochemistry and Cytochemistry'', 3(3), 212-226. * Hudson, P.B., Finkle, A.L., Hopkins, J.A., Sproul, E.E., Stout, A.P. (1954) Prostatic cancer. XI. Early prostatic cancer diagnosed by arbitrary open perineal biopsy among 300 unselected patients. ''Cancer'', 7(4), 690-703. * Hudson, P.B., Finkle, A.L., Trifilio, A., Jost, H.M., Sproul E.E., Stout, A.P., (1954) Prostatic Cancer: VII. Detection of unsuspected adeno carcinoma in the aging male population. ''The Journal of the American Medical Association'', 155(5), 426-429. * Lattes, R., McDonald, J.J., Sproul, E.E. (1954) Non-chromaffin paraganglioma, of carotid body and orbit; report of a case. ''Annals of surgery'', 139(3), 382-384. * Lenz, M., Sproul, E.E. (1934) Carcinoma of the tongue with generalized metastases. ''The American Journal of Surgery'', 25(1), 102-106.


References

{{DEFAULTSORT:Sproul, Edith E. 1907 births 1999 deaths American pathologists Writers from Passaic, New Jersey 20th-century American physicians Columbia University Vagelos College of Physicians and Surgeons alumni Barnard College alumni