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Edestin, (also known as Edistin) is a highly-digestible, hexameric legumin protein with six subunits, and a seed storage protein, with a molecular weight of 310 kDa. This protein is primarily found in hemp seeds. Edestin is a
It has been discovered that there are seven cDNAs encoding edestin in Cannabis sativa L., the sequences are distinguished by globulin characteristic. There is a type 1 and type 2 of edestin that are both used in process of the development of hemp seeds. Edestin has been used to help the nutritional quality of plant consumption. Hemp seeds are considered to be fruits from hemp plants, and can be used in several different methods: medicine, food, fiber, or psychoactive adjuvants.
Commercial
globular protein
In biochemistry, globular proteins or spheroproteins are spherical ("globe-like") proteins and are one of the common protein types (the others being fibrous, disordered and membrane proteins). Globular proteins are somewhat water-soluble (formi ...
(biologically active) as opposed to fibrous protein
In molecular biology, fibrous proteins or scleroproteins are one of the three main classifications of protein structure (alongside globular and membrane proteins). Fibrous proteins are made up of elongated or fibrous polypeptide chains which fo ...
(structural). Though the human body can manufacture globular proteins from any protein source, it is much more efficient for the body to make globulins
The globulins are a family of globular proteins that have higher molecular weights than albumins and are insoluble in pure water but dissolve in dilute salt solutions. Some globulins are produced in the liver, while others are made by the immune ...
from locally digestible globular proteins.
Edestin has the unique ability to stimulate the manufacturing process of antibodies against invasive agents and contains a low aggravatory phosphor content (kidney ailments, etc.).
Globular proteins found in edestin (and in Alpha 1 globulins
Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood proteases and show significant inhibitor activity.
The alpha globulins typically have mol ...
, Alpha 2 globulins
Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood proteases and show significant inhibitor activity.
The alpha globulins typically have mol ...
, Beta globulins, and Gamma globulins
Gamma globulins are a class of globulins, identified by their position after serum protein electrophoresis. The most significant gamma globulins are immunoglobulins (antibodies), although some immunoglobulins are not gamma globulins, and some g ...
) are long peptide chains, precursors for biological proteins essential for life. Edestin is similar to serum globulin (blood plasma), and the biologically active protein of edestin is metabolized in the human body and capable of biosynthesizing:
* hormones (which regulate all the body processes),
*hemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocyt ...
(which transports oxygen, carbon dioxide, and nitric oxide),
* enzymes (which catalyze and control biochemical reactions),
* antibodies (immunoglobulins which fend off invading bacteria, viruses, and other pathogens, as well as toxins or antigens as they enter the body).
Edestin can also be broken down to edestan.
Hemp seed
It has been discovered that there are seven cDNAs encoding edestin in Cannabis sativa L., the sequences are distinguished by globulin characteristic. There is a type 1 and type 2 of edestin that are both used in process of the development of hemp seeds. Edestin has been used to help the nutritional quality of plant consumption. Hemp seeds are considered to be fruits from hemp plants, and can be used in several different methods: medicine, food, fiber, or psychoactive adjuvants.
Commercial hemp seeds
Hemp, or industrial hemp, is a botanical class of ''Cannabis sativa'' cultivars grown specifically for industrial or medicinal use. It can be used to make a wide range of products. Along with bamboo, hemp is among the fastest growing plants o ...
(for human consumption) contain an average 30-35% protein, of which 60-80% is edestin (the remainder being albumin
Albumin is a family of globular proteins, the most common of which are the serum albumins. All the proteins of the albumin family are water-soluble, moderately soluble in concentrated salt solutions, and experience heat denaturation. Albumins ...
). A particular strain of Korean hemp, Cheungsam, because it contains 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, has been suggested for utilization as "a superior antioxidative nutrient".
References
Seed storage proteins {{protein-stub